d₂-2-chloro-1-(phenyl)ethanone

Base Information

• Chemical Name: d₂-2-chloro-1-(phenyl)ethanone
• CAS No.: 944419-13-0
• Molecular Formula: C₈H₇ClO
• Molecular Weight: 156.58
• Mol file: 944419-13-0.mol

Synonyms:d₂-2-chloro-1-(phenyl)ethanone

Chemical Property of d₂-2-chloro-1-(phenyl)ethanone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of d₂-2-chloro-1-(phenyl)ethanone

There total 3 articles about d₂-2-chloro-1-(phenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → d2-2-chloro-1-(phenyl)ethanone (944419-13-0)

Guidance literature:

With tetradeuterioacetic acid; water-d2; for 0.666667h; Heating; microwave irradiation;

DOI:10.1021/jo070831o

Reference yield: 40.0%

2-chloro-1,3-diphenyl-propane-1,3-dione (4571-27-1) → 1,3-diphenylpropanedione (120-46-7,61346-73-4) + d2-2-chloro-1-(phenyl)ethanone (944419-13-0)

Guidance literature:

2-chloro-1,3-diphenyl-propane-1,3-dione; With [Cu(tris(2-pyridylmethyl)amine)(CH₃CN)](ClO₄)2; lithium hexamethyldisilazane; In diethyl ether; acetonitrile; for 48h; Inert atmosphere; Glovebox;

With water-d2; In diethyl ether; acetonitrile;

DOI:10.1039/d0dt04074f

Reference yield:

1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → 2-chloro-2-deuterio-1-phenyl-ethanone (943148-97-8) + d2-2-chloro-1-(phenyl)ethanone (944419-13-0)

Guidance literature:

With chloroform-d1; 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; at 20 ℃; for 12h;

DOI:10.1021/jo070307h

upstream raw materials:

1-chloroacetophenone

2-chloro-1,3-diphenyl-propane-1,3-dione