1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose

Base Information

• Chemical Name: 1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose
• CAS No.: 145828-15-5
• Molecular Formula: C₃₈H₃₁O₁₁P
• Molecular Weight: 694.631
• Mol file: 145828-15-5.mol

Synonyms:1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose

Chemical Property of 1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose

There total 1 articles about 1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

chlorophosphoric acid diphenyl ester (2524-64-3) + 1,3,5-tri-O-benzoyl-α-D-ribofuranoside (22224-41-5) → 1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose (145828-15-5)

Guidance literature:

With 1-methyl-1H-imidazole; In dichloromethane; 0 deg C to RT;

DOI:10.1021/jo00057a020

Reference yield: 95.0%

1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose (145828-15-5) → 3,5-di-O-benzoyl-2-O-(diphenylphosphoryl)-D-ribofuranosyl bromide

Guidance literature:

With hydrogen bromide; acetic acid; In dichloromethane; 4 deg C to RT;

DOI:10.1021/jo00057a020

Reference yield:

1,3,5-tri-O-benzoyl-2-O-(diphenylphosphoryl)-α-D-ribofuranose (145828-15-5) → C31H26O9P

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / HBr/HOAc / CH₂Cl₂ / 4 deg C to RT

2: hexabutylditin / benzene / 7 °C / Irradiation

With hydrogen bromide; bis(tri-n-butyltin); acetic acid; In dichloromethane; benzene;

DOI:10.1021/jo00057a020

upstream raw materials:

chlorophosphoric acid diphenyl ester

1,3,5-tri-O-benzoyl-α-D-ribofuranoside