Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate

Base Information

Chemical Name:Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate
CAS No.:947537-57-7
Molecular Formula:C₁₉H₃₉N₃O₉P₂
Molecular Weight:515.481
Hs Code.:

Synonyms:Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate

Suppliers and Price of Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate

There total 1 articles about Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 947537-55-5
1-(t-Butyloxycarbonyl)-4-(2-(4-hydroxy-4-oxo-butanoyloxy)ethyl)piperazine

: 80474-99-3
tetraethyl (aminomethylene)bis(phosphonate)

: 947537-57-7
Tetraethyl (4-(2-(piperazin-4-yl)ethoxy)-4-oxo-butanoylamino)methylene-1,1-bisphosphonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dmap / dichloromethane / 3 h / 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 20 °C

2.2: 13 cc of Dowex 1.x.2 Cl^- form resin

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; dmap; In dichloromethane;