benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine

Base Information

• Chemical Name: benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine
• CAS No.: 1340483-79-5
• Molecular Formula: C₂₃H₃₁N₅
• Molecular Weight: 377.533
• Mol file: 1340483-79-5.mol

Synonyms:benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine

Chemical Property of benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine

There total 1 articles about benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + trimethylsilylazide (4648-54-8) + 1,1,3,3-tetramethylbutane isonitrile (14542-93-9) + Benzhydrylamine (91-00-9) → benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine (1340483-79-5)

Guidance literature:

In methanol; at 80 ℃; for 1.5h; Inert atmosphere; Microwave irradiation; Sealed tube;

DOI:10.1016/j.bmc.2011.08.039

Reference yield: 89.0%

benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine (1340483-79-5) → benzhydryl-(1H-tetrazol-5-ylmethyl)amine hydrochloride (1340484-03-8)

Guidance literature:

With hydrogenchloride; In ethanol; for 8h; Reflux; Inert atmosphere;

DOI:10.1016/j.bmc.2011.08.039

Reference yield: 70.0%

benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine (1340483-79-5) → 1H-1,2,3,4-tetrazol-5-ylmethanamine hydrochloride (118764-13-9,150031-49-5)

Guidance literature:

benzhydryl-[1-(1,1,3,3-tetramethylbutyl)-1H-tetrazol-5-ylmethyl]amine; With triethylsilane; trifluoroacetic acid; for 4.5h; Reflux; Inert atmosphere;

With hydrogenchloride; In water;

DOI:10.1016/j.bmc.2011.08.039

upstream raw materials:

formaldehyd

trimethylsilylazide

1,1,3,3-tetramethylbutane isonitrile

Benzhydrylamine

Downstream raw materials:

benzhydryl-(1H-tetrazol-5-ylmethyl)amine hydrochloride

1H-1,2,3,4-tetrazol-5-ylmethanamine hydrochloride