[4-(1H-PYRROL-1-YL)PHENYL]METHANOL

Base Information

• Chemical Name: [4-(1H-PYRROL-1-YL)PHENYL]METHANOL
• CAS No.: 143426-51-1
• Molecular Formula: C11H11NO
• Molecular Weight: 173.214
• Hs Code.: 2933990090
• Mol file: 143426-51-1.mol

Synonyms:[4-(1H-Pyrrol-1-yl)phenyl]methanol;N-(4-Hydroxymethylphenyl)pyrrole;(4-Pyrrolylphenyl)methan-1-ol;

Chemical Property of [4-(1H-PYRROL-1-YL)PHENYL]METHANOL

Chemical Property:

• Vapor Pressure: 0.00013mmHg at 25°C
• Melting Point: 102-105 °C
• Refractive Index: 1.573
• Boiling Point: 320.7 °C at 760 mmHg
• PKA: 14.02±0.10(Predicted)
• Flash Point: 147.7 °C
• PSA: 25.16000
• Density: 1.07 g/cm³
• LogP: 1.96960

Purity/Quality:

99%, ^*data from raw suppliers

[4-(1H-Pyrrol-1-yl)phenyl]methanol 95% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [4-(1H-PYRROL-1-YL)PHENYL]METHANOL

There total 4 articles about [4-(1H-PYRROL-1-YL)PHENYL]METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-(4-ethoxycarbonylphenyl)pyrrole (5044-37-1) → [4-(1H-pyrrol-1-yl)phenyl]methanol (143426-51-1)

Guidance literature:

1-(4-ethoxycarbonylphenyl)pyrrole; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; water; ethyl acetate; at 0 ℃;

Reference yield: 84.9%

1-(4-chlorophenyl)-1H-pyrrole (5044-38-2) + potassium (acetoxymethyl)trifluoroborate → [4-(1H-pyrrol-1-yl)phenyl]methanol (143426-51-1)

Guidance literature:

With sodium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; ruphos; In 1,4-dioxane; water; for 48h; Inert atmosphere; Reflux;

DOI:10.1021/ol300149b

Reference yield:

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → [4-(1H-pyrrol-1-yl)phenyl]methanol (143426-51-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sulfuric acid / 5 h / Reflux

2.1: acetic acid / 1 h / Reflux

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C

3.2: 0 °C

With lithium aluminium tetrahydride; sulfuric acid; acetic acid; In tetrahydrofuran;

upstream raw materials:

1-(4-ethoxycarbonylphenyl)pyrrole

1-(4-chlorophenyl)-1H-pyrrole

4-amino-benzoic acid

p-aminoethylbenzoate

Downstream raw materials:

1-(4’-formylphenyl)pyrrole

1-(4-chloromethylphenyl)-1H-pyrrole

1-[4-(bromomethyl)phenyl]-1H-pyrrole

4-(4-(pyrrol-1-yl)benzyloxy)benzaldehyde

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 143426-51-1 [4-(1H-PYRROL-1-YL)PHENYL]METHANOL

Send

Send

Metric Ton KG G Pound L ML

Send

Send