5044-38-2

Basic information

• Product Name: 1-(4-CHLOROPHENYL)-1H-PYRROLE
• Synonyms: 1-(4-CHLOROPHENYL)-1H-PYRROLE;1-(4-CHLOROPHENYL)PYRROLE;1-(4-CHLOROPHENYL)PYRROLE 98%;1-(4-Chlorophenyl)-1H-pyrrole,98%;1-(4-Chlorophenyl)-1H-pyrrole 97%
• CAS NO: 5044-38-2
• Molecular Formula: C₁₀H₈ClN
• Molecular Weight: 177.63
• Product Categories: PyrrolesHeterocyclic Building Blocks;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrroles
• Mol File: 5044-38-2.mol
• Article Data: 50

Chemical Properties

• Melting Point: 88-91 °C(lit.)
• Boiling Point: 200-203 °C (95.2627 mmHg)
• Flash Point: 113.8°C
• Appearance: /
• Density: 1.1810 (rough estimate)
• Vapor Pressure: 0.0157mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• PKA: -5.87±0.70(Predicted)
• CAS DataBase Reference: 1-(4-CHLOROPHENYL)-1H-PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLOROPHENYL)-1H-PYRROLE(5044-38-2)
• EPA Substance Registry System: 1-(4-CHLOROPHENYL)-1H-PYRROLE(5044-38-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 5044-38-2(Hazardous Substances Data)

Usage

Chemical Properties

yellowish crystalline powder

InChI:InChI=1/C10H8ClN/c11-9-3-5-10(6-4-9)12-7-1-2-8-12/h1-8H

Upstream product

• 526-99-8 meso-galactaric acid 
• 106-47-8 4-chloro-aniline 
• 110-00-9 furan 
• 3296-05-7 1-azido-4-chlorobenzene 
• 20484-61-1 TCNE-1-(p-Chlorphenyl)-pyrrol-Komplex 
• 20484-56-4 Chloranil-1-(p-Chlorphenyl)-pyrrol-Komplex 
• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 243988-27-4 N¹,N⁴-dimethoxy-N¹,N⁴-dimethylsuccinamide 
• 30438-94-9 N,N-diallyl-4-chlorobenzenamine 
• 6117-80-2 1,4-butenediol 
• 100-00-5 4-chlorobenzonitrile 
• 110-65-6 1,4-dihydroxybut-2-yne 
• 108-44-1 1-amino-3-methylbenzene 
• 28192-10-1 1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole 

Downstream Products

• 19867-89-1 2-(4-chlorophenyl)-1H-pyrrole 
• 55540-33-5 1-(2-carboxy-4-chlorophenyl)pyrrole 
• 53242-68-5 2-chloro-5-(1H-pyrrol-1-yl)benzoic acid 
• 354115-82-5 1-(2-Carboxy-4-chlorophenyl)pyrrole-2-carboxylic acid 
• 959706-68-4 2-[4-(1H-pyrrol-1-yl)phenyl]hexanal 
• 1063960-59-7 1-(4-cyclopropylphenyl)-1H-pyrrole 
• 1063961-21-6 1-(4-cyclobutylphenyl)-1H-pyrrole 
• 1086975-18-9 potassium 5-(4-(1H-pyrrol-1-yl)phenyl)pentyltrifluoroborate 
• 1086975-20-3 potassium (6-(4-(1H-pyrrol-1-yl)phenyl)hexyloxy)methyltrifluoroborate 
• 1086975-10-1 potassium 2-(4-(4-(1H-pyrrol-1-yl)phenyl)butyl)phenyltriflurorborate 
• 1086975-08-7 potassium 4-(4-(4-(1H-pyrrol-1-yl)phenyl)butyl)phenyltriflurorborate 
• 1086975-22-5 potassium 4-((5-(4-(1H-pyrrol-1-yl)phenyl)pentyloxy)methyl)phenyltrifluoroborate 
• 1086975-16-7 potassium 4-(1H-pyrrol-1-yl)phenethyltrifluoroborate 
• 1027334-72-0 1-(4-(benzyloxymethyl)phenyl)-1H-pyrrole 

Relevant articles and documents

Utilization of caffeine carbon supported cobalt catalyst in the tandem synthesis of pyrroles from nitroarenes and alkenyl diols

Employing bio-waste caffeine carbon-supported heterogeneous cobalt catalyst, synthesis of various substituted pyrrole derivatives is reported. In this methodology, pyrroles were synthesized through coupling between nitroarenes and alkenyl diols in a tandem manner. Among all the heterogeneous catalysts Co(OAc)2-CC-800 displayed the highest catalytic activity. Preparative scale synthesis of pyrroles and synthesis of anti-tubercular agent 5-(4-(1H-pyrrol-1-yl)phenyl)-1,3,4-oxadiazole-2-thiol revealed the practical applicability of this protocol. Several kinetic experiments and Hammett studies were conducted to understand the probable mechanism and electronic effects on this transformation.

Synergistic catalysis for light-driven proton reduction using a polyoxometalate-based Cu-Ni heterometallic-organic framework

Synergistic effects of bimetallic Ni and Cu supported on metal-organic polymer composites based on Wells-Dawson P2W18O626- clusters as photosensitizer units were identified, and we report a novel approach for addressing these issues for dehydrogenation and hydrogen production reactions.

Solvent Free Synthesis of N-Substituted Pyrroles Catalyzed by Calcium Nitrate

Moderated and mild way for synthesizing N-substituted pyrrole has been demonstrated herein. No solvents need to be used for this reaction, and instead, reactants themselves acted as a reaction medium. In fact, the reaction is carried out using catalytic amount of Ca(NO3)2.4H2O. The reaction conditions are selective and mild that helped to tolerate a wide variety of functional groups to give the desired products in good chemical yields.