Technology Process of 1-benzyl-3-acetyl-4-(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl) methyl pyridinium bromide
There total 9 articles about 1-benzyl-3-acetyl-4-(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl) methyl pyridinium bromide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
dichloromethane;
for 12h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) / toluene / 0.25 h / 20 °C / Inert atmosphere
1.2: 2 h / 110 °C
2.1: dichloromethane / 12 h / Reflux
With
triphenylphosphine; bis(dibenzylideneacetone)-palladium(0);
In
dichloromethane; toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / mineral oil; tetrahydrofuran / 1.5 h / Reflux
1.2: 3 h / 20 °C / Reflux; Inert atmosphere
2.1: potassium carbonate; sodium iodide / acetone / 6 h / Reflux
3.1: water; potassium hydroxide / ethanol / 0.5 h / Reflux
4.1: triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) / toluene / 0.25 h / 20 °C / Inert atmosphere
4.2: 2 h / 110 °C
5.1: dichloromethane / 12 h / Reflux
With
water; sodium hydride; potassium carbonate; triphenylphosphine; sodium iodide; potassium hydroxide; bis(dibenzylideneacetone)-palladium(0);
In
tetrahydrofuran; ethanol; dichloromethane; acetone; toluene; mineral oil;