dimethylphenylsilylethyl-d5 ether

Base Information

• Chemical Name: dimethylphenylsilylethyl-d5 ether
• CAS No.: 1252913-98-6
• Molecular Formula: C₁₀H₁₆OSi
• Molecular Weight: 185.282
• Mol file: 1252913-98-6.mol

Synonyms:dimethylphenylsilylethyl-d5 ether

Chemical Property of dimethylphenylsilylethyl-d5 ether

Chemical Property:

Purity/Quality:

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• Hazard Codes: 

MSDS Files:

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Technology Process of dimethylphenylsilylethyl-d5 ether

There total 4 articles about dimethylphenylsilylethyl-d5 ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

ethanol-d6 (1516-08-1) + 1-(dimethylphenylsilyl)-3,3-dimethyl-2-butyl trifluoroacetate (1252913-80-6) → tert-butylethylene (558-37-2) + dimethylphenylsilylethyl-d5 ether (1252913-98-6) + (E)-(3,3-dimethylbut-1-en-1-yl)dimethylphenylsilane (97779-83-4)

Guidance literature:

With 2,6-dimethylpyridine; at 55 ℃; Solvolysis; aq. buffer;

DOI:10.1002/poc.1667

Reference yield:

chloromethyldimethylphenylsilane (1833-51-8) → dimethylphenylsilylethyl-d5 ether (1252913-98-6) + (E)-(3,3-dimethylbut-1-en-1-yl)dimethylphenylsilane (97779-83-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: magnesium / diethyl ether

1.2: 3 h / 0 - 20 °C

2.1: pyridine / diethyl ether / 2 h / 0 °C

3.1: 2,6-dimethylpyridine / 55 °C / Solvolysis; aq. buffer

With pyridine; 2,6-dimethylpyridine; magnesium; In diethyl ether; 1.2: Grignard reaction;

DOI:10.1002/poc.1667

Reference yield:

bromobenzene (108-86-1,52753-63-6) → dimethylphenylsilylethyl-d5 ether (1252913-98-6) + (E)-(3,3-dimethylbut-1-en-1-yl)dimethylphenylsilane (97779-83-4)

Guidance literature:

Multi-step reaction with 4 steps

2.1: magnesium / diethyl ether

2.2: 3 h / 0 - 20 °C

3.1: pyridine / diethyl ether / 2 h / 0 °C

4.1: 2,6-dimethylpyridine / 55 °C / Solvolysis; aq. buffer

With pyridine; 2,6-dimethylpyridine; magnesium; In diethyl ether; 1.1: Grignard reaction / 2.2: Grignard reaction;

DOI:10.1002/poc.1667

upstream raw materials:

bromobenzene

1-(dimethylphenylsilyl)-3,3-dimethyl-2-butanol

ethanol-d6

1-(dimethylphenylsilyl)-3,3-dimethyl-2-butyl trifluoroacetate