1-Cyclohexyl-2,2-dimethyl-1-propanol

Base Information

• Chemical Name: 1-Cyclohexyl-2,2-dimethyl-1-propanol
• CAS No.: 15972-13-1
• Molecular Formula: C₁₁H₂₂O
• Molecular Weight: 170.295
• European Community (EC) Number: 844-845-0
• DSSTox Substance ID: DTXSID50977591
• Mol file: 15972-13-1.mol

Synonyms:1-Cyclohexyl-2,2-dimethyl-1-propanol;1-cyclohexyl-2,2-dimethylpropan-1-ol;62039-14-9;15972-13-1;ETHYLL-LACTATE;SCHEMBL8976097;DTXSID50977591;SHNBWIOMPFKTMH-UHFFFAOYSA-N;AKOS010015256;CS-0239902;FT-0758260;EN300-220826;Z513751738

Chemical Property of 1-Cyclohexyl-2,2-dimethyl-1-propanol

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 170.167065321
• Heavy Atom Count: 12
• Complexity: 128

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)C(C1CCCCC1)O

Technology Process of 1-Cyclohexyl-2,2-dimethyl-1-propanol

There total 4 articles about 1-Cyclohexyl-2,2-dimethyl-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethyl-1-phenylpropan-1-ol (3835-64-1) → 1-Cyclohexyl-2,2-dimethyl-1-propanol (15972-13-1,62039-14-9)

Guidance literature:

With hydrogen; Rh on carbon; In ethanol; at 25 ℃; under 105913 Torr;

Reference yield:

2,2-dimethylpropiophenone (938-16-9) → 2,2-dimethyl-1-phenylpropan-1-ol (3835-64-1) + 1-cyclohexyl-2,2-dimethyl-1-propanone (15963-60-7) + 1-Cyclohexyl-2,2-dimethyl-1-propanol (15972-13-1,62039-14-9)

Guidance literature:

With Rh*C₄H₈O*C₁₈H₁₅P; hydrogen; In tetrahydrofuran; at 30 ℃; for 5h; under 15001.5 Torr; Reagent/catalyst; Autoclave; Glovebox;

DOI:10.1002/cctc.201402524

Reference yield:

1-cyclohexyl-2,2-dimethyl-1-propanone (15963-60-7) → 1-Cyclohexyl-2,2-dimethyl-1-propanol (15972-13-1,62039-14-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Rh catalyst / benzene

2: NaOMe / methanol

With sodium methylate; Rh catalyst; In methanol; benzene;

DOI:10.1016/S0022-328X(00)92750-5

upstream raw materials:

2,2-dimethyl-1-phenylpropan-1-ol

(1-Cyclohexyl-2,2-dimethyl-propoxy)-diphenyl-silane

1-cyclohexyl-2,2-dimethyl-1-propanone

2,2-dimethylpropiophenone