1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

Base Information

Chemical Name:1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline
CAS No.:849092-83-7
Molecular Formula:C₂₂H₂₃ClN₂O₂S
Molecular Weight:414.956
Hs Code.:

1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1<i>H</i>-β-carboline

Synonyms:1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

Suppliers and Price of 1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

There total 4 articles about 1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 849092-82-6
N-(5-chloro-pent-1-ynyl)-N-[2-(1H-indol-3-yl)-ethyl]-4-methyl-benzenesulfonamide

: 849092-83-7
1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

Guidance literature:: With p-nitrobenzenesulfonic acid; In toluene; at 90 ℃; for 0.0833333h;
DOI:10.1021/ol0473391

Reference yield:

: 61-54-1
tryptamine

: 849092-83-7
1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / Et₃N / tetrahydrofuran

2: 48 percent / K₃PO₄; CuSO₄*5H₂O; 1,10-phenanthroline / toluene / 47 h / 75 °C

3: 56 percent / p-nitrobenzenesulfonic acid / toluene / 0.08 h / 90 °C

With potassium phosphate; 1,10-Phenanthroline; p-nitrobenzenesulfonic acid; copper(II) sulfate; triethylamine; In tetrahydrofuran; toluene; 3: Pictet-Spengler cyclization;
DOI:10.1021/ol0473391

Reference yield:

: 86658-78-8
N-tosyl tryptamine

: 849092-83-7
1-(4-chloro-butylidene)-2-(toluene-4-sulfonyl)-2,3,4,9-tetrahydro-1H-β-carboline

Guidance literature:: Multi-step reaction with 2 steps

1: 48 percent / K₃PO₄; CuSO₄*5H₂O; 1,10-phenanthroline / toluene / 47 h / 75 °C

2: 56 percent / p-nitrobenzenesulfonic acid / toluene / 0.08 h / 90 °C

With potassium phosphate; 1,10-Phenanthroline; p-nitrobenzenesulfonic acid; copper(II) sulfate; In toluene; 2: Pictet-Spengler cyclization;
DOI:10.1021/ol0473391