N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine

Base Information

• Chemical Name: N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine
• CAS No.: 426833-33-2
• Molecular Formula: C₂₅H₃₈N₄O₆S₂
• Molecular Weight: 554.732
• Mol file: 426833-33-2.mol

Synonyms:N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine

Chemical Property of N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine

There total 3 articles about N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

p-toluenesulfonyl chloride (98-59-9) + N,N-bis(2-aminoethyl)-N-[2-(N-t-butoxycarbonylamino)ethyl]amine (179167-09-0) → N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine (426833-33-2)

Guidance literature:

With triethylamine; In acetonitrile; at 20 ℃; for 17.0833h; Inert atmosphere;

DOI:10.1016/j.bmc.2008.11.011

Reference yield:

2,2',2''-triaminotriethylamine (4097-89-6) → N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine (426833-33-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N

With triethylamine;

DOI:10.1039/b314006g

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine (426833-33-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / CH₂Cl₂ / -78 - 20 °C

2: 64 percent / K₂CO₃ / acetonitrile / 23 h / 20 °C

With potassium carbonate; In dichloromethane; acetonitrile;

DOI:10.1021/jo016416s

upstream raw materials:

p-toluenesulfonyl chloride

N,N-bis(2-aminoethyl)-N-[2-(N-t-butoxycarbonylamino)ethyl]amine

2,2',2''-triaminotriethylamine

di-tert-butyl dicarbonate

Downstream raw materials:

N,N′-(((2-aminoethyl)azanediyl)bis(ethane-2,1-diyl))bis(4-methylbenzenesulfonamide)