4-acetyl-4-benzylpimelic acid

Base Information

• Chemical Name: 4-acetyl-4-benzylpimelic acid
• CAS No.: 350252-92-5
• Molecular Formula: C₁₆H₂₀O₅
• Molecular Weight: 292.332
• Mol file: 350252-92-5.mol

Synonyms:4-acetyl-4-benzylpimelic acid

Chemical Property of 4-acetyl-4-benzylpimelic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-acetyl-4-benzylpimelic acid

There total 2 articles about 4-acetyl-4-benzylpimelic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-acetyl-4-benzylpimelonitrile (350252-91-4) → 4-acetyl-4-benzylpimelic acid (350252-92-5)

Guidance literature:

With potassium hydroxide; In water; for 24h; Heating;

DOI:10.1016/S0040-4020(01)00172-7

Reference yield:

4-Phenyl-2-butanone (2550-26-7) → 4-acetyl-4-benzylpimelic acid (350252-92-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / potassium hydroxide / methanol; 2-methyl-propan-2-ol / 1 h

2: 84 percent / potassium hydroxide / H₂O / 24 h / Heating

With potassium hydroxide; In methanol; water; tert-butyl alcohol;

DOI:10.1016/S0040-4020(01)00172-7

Reference yield: 61.0%

4-acetyl-4-benzylpimelic acid (350252-92-5) → 4-acetyl-4-benzylcyclohexanone (350252-93-6)

Guidance literature:

4-acetyl-4-benzylpimelic acid; With pyridine; acetic anhydride; for 2h; Heating;

under 1 - 3 Torr; Heating;

DOI:10.1016/S0040-4020(01)00172-7

upstream raw materials:

4-acetyl-4-benzylpimelonitrile

4-Phenyl-2-butanone

Downstream raw materials:

4-acetyl-4-benzylcyclohexanone

4-acetyl-4-benzyl-1-morpholinocyclohexene