4-acetyl-4-benzylpimelonitrile

Base Information

• Chemical Name: 4-acetyl-4-benzylpimelonitrile
• CAS No.: 350252-91-4
• Molecular Formula: C₁₆H₁₈N₂O
• Molecular Weight: 254.332
• Mol file: 350252-91-4.mol

Synonyms:4-acetyl-4-benzylpimelonitrile

Chemical Property of 4-acetyl-4-benzylpimelonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-acetyl-4-benzylpimelonitrile

There total 1 articles about 4-acetyl-4-benzylpimelonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

4-Phenyl-2-butanone (2550-26-7) + acrylonitrile (107-13-1,25014-41-9) → 4-acetyl-4-benzylpimelonitrile (350252-91-4)

Guidance literature:

With potassium hydroxide; In methanol; tert-butyl alcohol; for 1h;

DOI:10.1016/S0040-4020(01)00172-7

Reference yield: 84.0%

4-acetyl-4-benzylpimelonitrile (350252-91-4) → 4-acetyl-4-benzylpimelic acid (350252-92-5)

Guidance literature:

With potassium hydroxide; In water; for 24h; Heating;

DOI:10.1016/S0040-4020(01)00172-7

Reference yield:

4-acetyl-4-benzylpimelonitrile (350252-91-4) → 4-acetyl-4-benzylcyclohexanone (350252-93-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 84 percent / potassium hydroxide / H₂O / 24 h / Heating

2.1: acetic anhydride; pyridine / 2 h / Heating

2.2: 61 percent / 1 - 3 Torr / Heating

With pyridine; potassium hydroxide; acetic anhydride; In water;

DOI:10.1016/S0040-4020(01)00172-7

upstream raw materials:

4-Phenyl-2-butanone

acrylonitrile

Downstream raw materials:

4-acetyl-4-benzylpimelic acid

4-acetyl-4-benzylcyclohexanone

4-acetyl-4-benzyl-1-morpholinocyclohexene