benzyl 3,5-dimethyl-4-isoxazolyl ketone

Base Information

• Chemical Name: benzyl 3,5-dimethyl-4-isoxazolyl ketone
• CAS No.: 81022-81-3
• Molecular Formula: C₁₃H₁₃NO₂
• Molecular Weight: 215.252
• Mol file: 81022-81-3.mol

Synonyms:benzyl 3,5-dimethyl-4-isoxazolyl ketone

Chemical Property of benzyl 3,5-dimethyl-4-isoxazolyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl 3,5-dimethyl-4-isoxazolyl ketone

There total 1 articles about benzyl 3,5-dimethyl-4-isoxazolyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

3,5-dimethyl-4-phenylethynylisoxazole (81022-96-0) → 3,5-dimethyl-4-isoxazolylmethyl phenyl ketone (81033-28-5) + benzyl 3,5-dimethyl-4-isoxazolyl ketone (81022-81-3)

Guidance literature:

With water; sulfuric acid; mercury(II) sulfate; In acetone; for 27.5h; Heating;

Reference yield: 94.0%

benzyl 3,5-dimethyl-4-isoxazolyl ketone (81022-81-3) → benzyl 3,5-dimethyl-4-isoxazolyl ketone oxime (81023-00-9)

Guidance literature:

With potassium hydroxide; hydroxylamine hydrochloride; In methanol; water; for 42h; Heating;

Reference yield:

benzyl 3,5-dimethyl-4-isoxazolyl ketone (81022-81-3) → N-benzyl-3,5-dimethylisoxazole-4-carboxamide (81022-87-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / KOH, HONH₂*HCl / methanol; H₂O / 42 h / Heating

2: 19 percent / PCl₅ / diethyl ether / 20 h / Ambient temperature; adding, 0-5 deg C

With potassium hydroxide; phosphorus pentachloride; hydroxylamine hydrochloride; In methanol; diethyl ether; water;

upstream raw materials:

3,5-dimethyl-4-phenylethynylisoxazole

Downstream raw materials:

benzyl 3,5-dimethyl-4-isoxazolyl ketone oxime

N-benzyl-3,5-dimethylisoxazole-4-carboxamide

N-(3,5-dimethyl-4-isoxazolyl)phenylacetamide