(S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one

Base Information

• Chemical Name: (S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one
• CAS No.: 207983-99-1
• Molecular Formula: C₂₀H₃₀O₂S
• Molecular Weight: 334.523
• Mol file: 207983-99-1.mol

Synonyms:(S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one

Chemical Property of (S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one

There total 2 articles about (S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(E)-3-((S)-2,4,6-Triisopropyl-benzenesulfinyl)-pent-3-en-2-ol (207983-93-5) → (S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one (207983-99-1)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; water; In acetone; at 0 ℃;

DOI:10.1039/a800828k

Reference yield:

(R,E/Z)-Prop-1-enyl 2,4,6-triisopropylphenyl sulfoxide → (S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one (207983-99-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / LDA / tetrahydrofuran / 1.) -100 deg C, 2 min, 2.) -100 deg C, 15 min

2: 72 percent / CrO₃, H₂SO₄, H₂O / acetone / 0 °C

With chromium(VI) oxide; sulfuric acid; water; lithium diisopropyl amide; In tetrahydrofuran; acetone;

DOI:10.1039/a800828k

Reference yield: 99.0%

2-iodo-propane (75-30-9) + (S,E)-3-[(2,4,6-triisopropylphenyl)sulfinyl]-3-pentene-2-one (207983-99-1) → 4,5-Dimethyl-3-(2,4,6-triisopropylphenylsulfanyl)hex-3-en-2-one

Guidance literature:

With air; triethyl borane; toluene-4-sulfonic acid; In dichloromethane; at 0 ℃; for 0.7h;

DOI:10.1039/a800828k

upstream raw materials:

(E)-3-((S)-2,4,6-Triisopropyl-benzenesulfinyl)-pent-3-en-2-ol

Downstream raw materials:

(3R,4R,R_S)-5,5-ethylenedioxy-4-methyl-3-[(2,4,6-triisopropylphenyl)sulfinyl]-2-pentanone

(S)-2-methyl-4-oxopentanal