(3S)-3-Amino-4,4-dimethyloxolan-2-one

Base Information

Chemical Name:(3S)-3-Amino-4,4-dimethyloxolan-2-one
CAS No.:157717-59-4
Molecular Formula:C₆H₁₁NO₂
Molecular Weight:129.159
Hs Code.:
DSSTox Substance ID:DTXSID601243025
Mol file:157717-59-4.mol

Synonyms:(3S)-3-Amino-4,4-dimethyloxolan-2-one;157717-59-4;2(3H)-Furanone,3-aminodihydro-4,4-dimethyl-,(3S)-(9CI);SCHEMBL14240875;DTXSID601243025;EN300-1074321;(3S)-3-Aminodihydro-4,4-dimethyl-2(3H)-furanone

Suppliers and Price of (3S)-3-Amino-4,4-dimethyloxolan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (3S)-3-Amino-4,4-dimethyloxolan-2-one

Chemical Property:

PSA：52.32000
LogP:0.59700
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:129.078978594
Heavy Atom Count:9
Complexity:142

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(COC(=O)C1N)C
Isomeric SMILES:CC1(COC(=O)[C@H]1N)C

Technology Process of (3S)-3-Amino-4,4-dimethyloxolan-2-one

There total 3 articles about (3S)-3-Amino-4,4-dimethyloxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 956904-51-1
(R)-(+)-3-dibenzylamino-4,4-dimethyldihydrofuran-2-one

: 368436-80-0,157717-59-4
3(R)-amino-4,4-dimethyl-2-oxo-tetrahydrofuran

Guidance literature:: With formic acid; palladium on activated charcoal; In methanol; at 40 ℃; for 2h;
DOI:10.1016/j.tetasy.2007.07.033

Reference yield:

: C₂₇H₂₉NO₂S

: 368436-80-0,157717-59-4
3(R)-amino-4,4-dimethyl-2-oxo-tetrahydrofuran

Guidance literature:: Multi-step reaction with 3 steps

1: m-CPBA / CH₂Cl₂ / 0.5 h / 20 °C

2: 37.5 mg / i-PrMgCl / tetrahydrofuran / 0.25 h / -78 °C

3: HCOOH / Pd/C / methanol / 2 h / 40 °C

With formic acid; isopropylmagnesium chloride; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/j.tetasy.2007.07.033

Reference yield:

: C₂₇H₂₉NO₃S

: 368436-80-0,157717-59-4
3(R)-amino-4,4-dimethyl-2-oxo-tetrahydrofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 37.5 mg / i-PrMgCl / tetrahydrofuran / 0.25 h / -78 °C

2: HCOOH / Pd/C / methanol / 2 h / 40 °C

With formic acid; isopropylmagnesium chloride; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/j.tetasy.2007.07.033