Ethyl 2-bromo-2-(4-iodophenyl)acetate

Base Information

Chemical Name:Ethyl 2-bromo-2-(4-iodophenyl)acetate
CAS No.:15250-48-3
Molecular Formula:C₁₀H₁₀BrIO₂
Molecular Weight:368.997
Hs Code.:
DSSTox Substance ID:DTXSID901297419

Synonyms:Ethyl 2-bromo-2-(4-iodophenyl)acetate;15250-48-3;DTXSID901297419;Ethyl alpha-bromo-4-iodobenzeneacetate

Suppliers and Price of Ethyl 2-bromo-2-(4-iodophenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 2-bromo-2-(4-iodophenyl)acetate

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:367.89089
Heavy Atom Count:14
Complexity:191

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(C1=CC=C(C=C1)I)Br

Technology Process of Ethyl 2-bromo-2-(4-iodophenyl)acetate

There total 4 articles about Ethyl 2-bromo-2-(4-iodophenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: ethyl 2-diazo-2-(4-iodophenyl)acetate

: 15250-48-3
(+/-)-α-bromo-(4-iodophenyl)acetic acid ethyl ester

Guidance literature:: With cobalt(II) bromide hexahydrate; In 1,4-dioxane; at 100 ℃; for 1h; Inert atmosphere;
DOI:10.1002/adsc.202000009

Reference yield:

: 15250-46-1
ethyl (4-iodophenyl)acetate

: 15250-48-3
(+/-)-α-bromo-(4-iodophenyl)acetic acid ethyl ester

Guidance literature:: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; for 5h; Heating;
DOI:10.1021/jm050257d

Reference yield:

: 1798-06-7
(4-iodophenyl)acetic acid

: 15250-48-3
(+/-)-α-bromo-(4-iodophenyl)acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / H₂SO₄ / 5 h / Heating

2: N-bromosuccinimide; AIBN / CCl₄ / 5 h / Heating

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); sulfuric acid; In tetrachloromethane;
DOI:10.1021/jm050257d