2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile

Base Information

Chemical Name:2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile
CAS No.:103523-64-4
Molecular Formula:C₂₅H₃₄N₂O₃
Molecular Weight:410.557
Hs Code.:

Synonyms:2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile

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Chemical Property of 2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile

Chemical Property:

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Technology Process of 2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile

There total 4 articles about 2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19924-43-7
3-methoxyphenylacetonitrile

: 103523-64-4
2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaNH₂ / 1.) THF, 0.5 h, room temp. 2.) THF, 4 h, room temp.

2: 1.) NaNH₂

3: aq. (COOH)2

4: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium tetrahydroborate; oxalic acid; sodium amide;
DOI:10.1248/cpb.36.373

Reference yield:

: 26056-32-6
2-(3-anisyl)-3-methylbutanonitrile

: 103523-64-4
2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaNH₂

2: aq. (COOH)2

3: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium tetrahydroborate; oxalic acid; sodium amide;
DOI:10.1248/cpb.36.373

Reference yield:

: 5,5-Diethoxy-2-isopropyl-2-(3-methoxy-phenyl)-pentanenitrile

: 103523-64-4
2-Isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-2-(3-methoxy-phenyl)-pentanenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: aq. (COOH)2

2: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium tetrahydroborate; oxalic acid;
DOI:10.1248/cpb.36.373