N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide

Base Information

Chemical Name:N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide
CAS No.:1300729-13-8
Molecular Formula:C₂₄H₂₃N₃O₃S
Molecular Weight:433.531
Hs Code.:

Synonyms:N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide

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Chemical Property of N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide

Chemical Property:

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Technology Process of N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide

There total 6 articles about N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₄₃H₃₇N₃O₃S

: 1300729-13-8
N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide

Guidance literature:: C₄₃H₃₇N₃O₃S; With acetic acid; In methanol; at 80 ℃; for 2h;

With sodium hydroxide; In methanol; water;

Reference yield:

: 104-10-9
2-(4'-aminophenyl)ethyl alcohol

: 1300729-13-8
N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide

Guidance literature:: Multi-step reaction with 6 steps

1.1: acetic acid / 1 h / 100 °C

2.1: pyridine / dichloromethane / 16 h / 0 - 20 °C

3.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C

3.2: Inert atmosphere

4.1: hydrazine hydrate / ethanol / 2 h / 80 °C

5.1: pyridine / dichloromethane / 16 h / 20 °C

6.1: acetic acid / methanol / 2 h / 80 °C

With pyridine; sodium hydride; hydrazine hydrate; acetic acid; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: C₄₄H₃₃N₃O₃

: 1300729-13-8
N-(4-(2-(2-(1H-imidazol-4-yl)phenoxy)ethyl)phenyl)-1-phenylmethanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / ethanol / 2 h / 80 °C

2: pyridine / dichloromethane / 16 h / 20 °C

3: acetic acid / methanol / 2 h / 80 °C

With pyridine; hydrazine hydrate; acetic acid; In methanol; ethanol; dichloromethane;