1-benzyl-5-chloroisatin

Base Information

• Chemical Name: 1-benzyl-5-chloroisatin
• CAS No.: 26960-68-9
• Molecular Formula: C₁₅H₁₀ClNO₂
• Molecular Weight: 271.703
• Mol file: 26960-68-9.mol

Synonyms:1-benzyl-5-chloroisatin

Chemical Property of 1-benzyl-5-chloroisatin

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-5-chloroisatin

There total 13 articles about 1-benzyl-5-chloroisatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

5-chloroindole 2,3-dione (17630-76-1) + benzyl chloride (100-44-7) → 1-benzyl-5-chloroisatin (26960-68-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 48h; Temperature;

DOI:10.1248/bpb.b17-00674

Reference yield: 98.0%

5-chloroindole 2,3-dione (17630-76-1) + benzyl bromide (100-39-0) → 1-benzyl-5-chloroisatin (26960-68-9)

Guidance literature:

With potassium carbonate; In acetonitrile;

DOI:10.1016/j.tetlet.2015.09.125

Reference yield: 90.0%

→ 1-benzyl-5-chloroisatin (26960-68-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 0.0833333h; Microwave irradiation;

upstream raw materials:

5-chloroindole 2,3-dione

benzyl bromide

benzyl chloride

4-chloro-aniline

Downstream raw materials:

1-benzyl-5-chloroindolin-2-one

C₂₈H₂₀ClNO₄

(Z)-N'-(1-benzyl-5-chloro-2-oxoindolin-3-ylidene)isonicotinohydrazide

ethyl 1'-benzyl-5'-chloro-5,5-dicyano-2'-oxospiro[cyclopent[2]ene-1,3'-indoline]-2-carboxylate