Technology Process of C36H40N2O7S
There total 6 articles about C36H40N2O7S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
succinic acid anhydride; (S,Z)-allyl 1-((5-hydroxy-1-tritylthiopent-2-en-2-yl)(methyl)amino)-1-oxopropan-2-ylcarbamate;
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 4h;
With
hydrogenchloride;
In
water;
DOI:10.1021/ja204088a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: copper(l) iodide; caesium carbonate; N,N`-dimethylethylenediamine / 1,4-dioxane / 50 - 60 °C / Inert atmosphere; Sonication
2: diisopropyl azodicarboxylate; triphenylphosphine / dichloromethane / 20 °C / Inert atmosphere; Reflux
3: potassium carbonate / N,N-dimethyl-formamide / 48 h / 20 °C
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 - 20 °C
5: dmap; triethylamine / dichloromethane / 4 h / 20 °C
With
dmap; copper(l) iodide; diisopropyl azodicarboxylate; tetrabutyl ammonium fluoride; potassium carbonate; caesium carbonate; triethylamine; triphenylphosphine; N,N`-dimethylethylenediamine;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
2: Mitsunobu reaction;
DOI:10.1021/ja204088a
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: n-butyllithium / tetrahydrofuran; cyclohexane / 0.17 h / -23 °C / Inert atmosphere
1.2: 60 h / 35 °C / Inert atmosphere
1.3: 0.33 h / -78 °C / Inert atmosphere
2.1: copper(l) iodide; caesium carbonate; N,N`-dimethylethylenediamine / 1,4-dioxane / 50 - 60 °C / Inert atmosphere; Sonication
3.1: diisopropyl azodicarboxylate; triphenylphosphine / dichloromethane / 20 °C / Inert atmosphere; Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 48 h / 20 °C
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 - 20 °C
6.1: dmap; triethylamine / dichloromethane / 4 h / 20 °C
With
dmap; copper(l) iodide; n-butyllithium; diisopropyl azodicarboxylate; tetrabutyl ammonium fluoride; potassium carbonate; caesium carbonate; triethylamine; triphenylphosphine; N,N`-dimethylethylenediamine;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; cyclohexane; N,N-dimethyl-formamide;
3.1: Mitsunobu reaction;
DOI:10.1021/ja204088a
