(R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide

Base Information

• Chemical Name: (R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide
• CAS No.: 1356837-78-9
• Molecular Formula: C₁₇H₁₄ClN₃O₂
• Molecular Weight: 327.77
• Mol file: 1356837-78-9.mol

Synonyms:(R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide

Chemical Property of (R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide

There total 1 articles about (R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-chlorophenoxy)propionic acid (76466-16-5) + 2-(1H-pyrazol-3-yl)pyridine (75415-03-1,192777-54-1) → (R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide (1356837-78-9)

Guidance literature:

With thionyl chloride; triethylamine; In benzene; at 0 ℃; for 2h;

DOI:10.1002/chir.21024

Reference yield:

(R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide (1356837-78-9) → (R)-2-(2-chlorophenoxy) propanoic acid (25140-86-7,31460-41-0,31460-42-1,76466-16-5) + (S)-2-(2-chlorophenoxy) propanoic acid (25140-86-7,31460-41-0,31460-42-1,76466-16-5)

Guidance literature:

With water; In tert-butyl methyl ether; at 35 ℃; for 1h; optical yield given as %ee; enantioselective reaction; Enzymatic reaction;

DOI:10.1002/chir.21024

Reference yield:

(R,S)-2-(2-chlorophenoxy)propionyl 3-(2-pyridine)pyrazolide (1356837-78-9) → (S)-2-(2-chlorophenoxy) propanoic acid (25140-86-7,31460-41-0,31460-42-1,76466-16-5)

Guidance literature:

With water; In tert-butyl methyl ether; at 25 ℃; for 12h; optical yield given as %ee; enantioselective reaction; Enzymatic reaction;

DOI:10.1002/chir.21024

upstream raw materials:

2-(2-chlorophenoxy)propionic acid

2-(1H-pyrazol-3-yl)pyridine

Downstream raw materials:

(R)-2-(2-chlorophenoxy) propanoic acid

(S)-2-(2-chlorophenoxy) propanoic acid