(1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene

Base Information

• Chemical Name: (1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene
• CAS No.: 43219-56-3
• Molecular Formula: C₁₆H₂₄
• Molecular Weight: 216.367
• Mol file: 43219-56-3.mol

Synonyms:(1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene

Chemical Property of (1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene

There total 2 articles about (1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(2Z,4E)-3-methyl-5-[2,6,6-trimethylcyclohex-1-enyl]penta-2,4-dienal (54226-17-4) + Methyltriphenylphosphonium bromide (1779-49-3) → (1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene (43219-56-3)

Guidance literature:

Methyltriphenylphosphonium bromide; With sodium hydride; dimethyl sulfoxide; In pentane; at 20 ℃; for 0.25h; Inert atmosphere;

(2Z,4E)-3-methyl-5-[2,6,6-trimethylcyclohex-1-enyl]penta-2,4-dienal; at 5 - 10 ℃; for 0.166667h; Inert atmosphere;

diastereoselective reaction;

DOI:10.1016/j.tetlet.2012.07.122

Reference yield:

→ (1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene (43219-56-3)

Guidance literature:

6, 13;

DOI:10.1002/hlca.19730560524

Reference yield: 88.0%

(1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene (43219-56-3) + ethyl (2E,4E/Z)-3-methylhexa-2,4-dienoate → ethyl (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate (86708-67-0,24519-09-3)

Guidance literature:

With Hoveyda-Grubbs catalyst second generation; In toluene; at 20 ℃; for 16h; diastereoselective reaction;

DOI:10.1016/j.tetlet.2012.07.122

upstream raw materials:

(2Z,4E)-3-methyl-5-[2,6,6-trimethylcyclohex-1-enyl]penta-2,4-dienal

Methyltriphenylphosphonium bromide

Downstream raw materials:

ethyl (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate