1H-Pyrrolizine-1,2,7-triol, 3-(butylamino)methylhexahydro-, 1R-(1.alpha.,2.beta.,3.alpha.,7.beta.,7a.alpha.)-

Base Information

Chemical Name:1H-Pyrrolizine-1,2,7-triol, 3-(butylamino)methylhexahydro-, 1R-(1.alpha.,2.beta.,3.alpha.,7.beta.,7a.alpha.)-
CAS No.:156205-76-4
Molecular Formula:C₁₂H₂₄N₂O₃
Molecular Weight:244.334
Hs Code.:
Mol file:156205-76-4.mol

Synonyms:1H-Pyrrolizine-1,2,7-triol, 3-(butylamino)methylhexahydro-, 1R-(1.alpha.,2.beta.,3.alpha.,7.beta.,7a.alpha.)-

Suppliers and Price of 1H-Pyrrolizine-1,2,7-triol, 3-(butylamino)methylhexahydro-, 1R-(1.alpha.,2.beta.,3.alpha.,7.beta.,7a.alpha.)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1H-Pyrrolizine-1,2,7-triol, 3-(butylamino)methylhexahydro-, 1R-(1.alpha.,2.beta.,3.alpha.,7.beta.,7a.alpha.)-

Chemical Property:

Purity/Quality:

Safty Information:

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Useful:

Technology Process of 1H-Pyrrolizine-1,2,7-triol, 3-(butylamino)methylhexahydro-, 1R-(1.alpha.,2.beta.,3.alpha.,7.beta.,7a.alpha.)-

There total 7 articles about 1H-Pyrrolizine-1,2,7-triol, 3-(butylamino)methylhexahydro-, 1R-(1.alpha.,2.beta.,3.alpha.,7.beta.,7a.alpha.)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 109-73-9,85404-21-3
N-butylamine

: 156206-15-4
Methanesulfonic acid (1S,6S,7S,8R,8aR)-1,7,8-trihydroxy-octahydro-indolizin-6-yl ester

: 156205-71-9
6-O-methylcastanospermine

: 156205-76-4
8-butylamino-8-deoxyaustraline

: 156205-75-3
6-butylamino-6-deoxycastanospermine

: (1S,6R,7S,8S,8aR)-7-Butylamino-octahydro-indolizine-1,6,8-triol

Guidance literature:: at 50 - 80 ℃;
DOI:10.1016/S0040-4020(01)85075-4

Reference yield:

: 79831-76-8
(1S,6S,7R,8R,8aR)-2,6,7,8-tetrahydroxy-indolizidine

: 156205-76-4
8-butylamino-8-deoxyaustraline

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / pyridine / 0 deg C -> r.t., overnight

2: 30 percent / tributyltin methoxide / tetrahydrofuran / Heating

3: 86 percent / pyridine

4: NaOMe / tetrahydrofuran; methanol / Ambient temperature

5: 46 percent / 50 - 80 °C

With pyridine; sodium methylate; tributyltin methoxide; In tetrahydrofuran; pyridine; methanol;
DOI:10.1016/S0040-4020(01)85075-4

Reference yield:

: 156205-43-5
6-O-carboxybenzylcastenospermine

: 156205-76-4
8-butylamino-8-deoxyaustraline

Guidance literature:: Multi-step reaction with 5 steps

1: 76 percent / pyridine / Ambient temperature

2: 73 percent / H₂ / 5percent Pd/C / ethyl acetate; ethanol / 3102.9 Torr

3: 86 percent / pyridine

4: NaOMe / tetrahydrofuran; methanol / Ambient temperature

5: 46 percent / 50 - 80 °C

With pyridine; hydrogen; sodium methylate; palladium on activated charcoal; In tetrahydrofuran; pyridine; methanol; ethanol; ethyl acetate;
DOI:10.1016/S0040-4020(01)85075-4