4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine

Base Information

• Chemical Name: 4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine
• CAS No.: 5933-01-7
• Molecular Formula: C₁₅H₂₁NO
• Molecular Weight: 231.338
• Mol file: 5933-01-7.mol

Synonyms:4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine

Chemical Property of 4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine

There total 4 articles about 4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[ethyl-(1-methyl-1-phenyl-but-2-ynyl)-amino]-ethanol (5993-07-7) → 4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine (5933-01-7)

Guidance literature:

With potassium hydroxide; In xylene; for 4h; Heating;

DOI:10.1021/jo01339a026

Reference yield:

Aethyl-<1-methyl-1-phenyl-but-2-inyl>-amin (5933-13-1) → 4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine (5933-01-7)

Guidance literature:

Multi-step reaction with 2 steps

2: KOH / xylene / 4 h / Heating

With potassium hydroxide; In xylene;

DOI:10.1021/jo01339a026

Reference yield:

N-Aethyl-1-phenyl-1-methyl-propargylamin (805180-83-0) → 4-ethyl-5,7-dimethyl-5-phenyl-2,3,4,5-tetrahydro-[1,4]oxazepine (5933-01-7)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) NaNH₂, liq. NH₃, Et₂O, (ii) /BRN= 969135/

3: KOH / xylene / 4 h / Heating

With potassium hydroxide; In xylene;

DOI:10.1021/jo01339a026

upstream raw materials:

2-[ethyl-(1-methyl-1-phenyl-but-2-ynyl)-amino]-ethanol

Aethyl-<1-methyl-1-phenyl-but-2-inyl>-amin

N-Aethyl-1-phenyl-1-methyl-propargylamin

Downstream raw materials:

Aethyl-<2-(1-methyl-3-phenyl-butoxy)-aethyl>-amin