6,7,8-Indolizinetriol, 1-fluorooctahydro-, 1R-(1.alpha.,6.alpha.,7.beta.,8.alpha.,8a.alpha.)-

Base Information

Chemical Name:6,7,8-Indolizinetriol, 1-fluorooctahydro-, 1R-(1.alpha.,6.alpha.,7.beta.,8.alpha.,8a.alpha.)-
CAS No.:156198-81-1
Molecular Formula:C₈H₁₄FNO₃
Molecular Weight:191.202
Hs Code.:
Mol file:156198-81-1.mol

Synonyms:6,7,8-Indolizinetriol, 1-fluorooctahydro-, 1R-(1.alpha.,6.alpha.,7.beta.,8.alpha.,8a.alpha.)-

Suppliers and Price of 6,7,8-Indolizinetriol, 1-fluorooctahydro-, 1R-(1.alpha.,6.alpha.,7.beta.,8.alpha.,8a.alpha.)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6,7,8-Indolizinetriol, 1-fluorooctahydro-, 1R-(1.alpha.,6.alpha.,7.beta.,8.alpha.,8a.alpha.)-

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 6,7,8-Indolizinetriol, 1-fluorooctahydro-, 1R-(1.alpha.,6.alpha.,7.beta.,8.alpha.,8a.alpha.)-

There total 10 articles about 6,7,8-Indolizinetriol, 1-fluorooctahydro-, 1R-(1.alpha.,6.alpha.,7.beta.,8.alpha.,8a.alpha.)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (1R,6S,7R,8R,8aS)-1-Fluoro-6,7,8-tris-methoxymethoxy-octahydro-indolizine

: 156198-81-1,156150-82-2
1-deoxy-1-epi-1-fluorocastanospermine

Guidance literature:: With hydrogenchloride; In methanol; Yield given;
DOI:10.1016/S0040-4039(00)76852-3

Reference yield:

: (1S,6S,7R,8R,8aS)-1-Fluoro-6,7,8-tris-methoxymethoxy-octahydro-indolizine

: 156198-81-1,156150-82-2
1-deoxy-1-fluorocastanospermine

Guidance literature:: With hydrogenchloride; In methanol; Yield given;
DOI:10.1016/S0040-4039(00)76852-3

Reference yield:

: 156150-86-6
2,2-Dimethyl-propionic acid (1S,6S,7R,8R,8aS)-6,7,8-trihydroxy-octahydro-indolizin-1-yl ester

: 156198-81-1,156150-82-2
1-deoxy-1-epi-1-fluorocastanospermine

Guidance literature:: Multi-step reaction with 4 steps

1: ⁱPr₂NEt / toluene / 90 °C

2: LiAlH₄

3: Et₃N, diethylaminosulfur trifluoride

4: 20 percent conc. HCl / methanol

With hydrogenchloride; lithium aluminium tetrahydride; diethylamino-sulfur trifluoride; triethylamine; N-ethyl-N,N-diisopropylamine; In methanol; toluene;
DOI:10.1016/S0040-4039(00)76852-3