N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

Base Information

Chemical Name:N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide
CAS No.:308286-27-3
Molecular Formula:C₁₄H₁₂F₂N₄O₃
Molecular Weight:322.271
Hs Code.:

Synonyms:N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

Suppliers and Price of N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

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Technology Process of N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

There total 1 articles about N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.3%

: 17573-78-3
4,5,6-trifluoropyrimidine

: 156895-31-7
(2E)-2-(2-Hydroxyphenyl)-2-(methoxyimino)-N-methylethanamide

: 308286-27-3
N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

Reference yield: 57.8%

: 308286-28-4
N-methyl-(Z)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

: 308286-27-3
N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

: 3260-87-5
3-chloro-o-cresol

: (2E)-2-(2-{[6-(3-chloro-2-methylphenoxy)-5-fluoro-4-pyrimidinyl]oxy}phenyl)-2-(methoxyimino)-N-methylethanamide

: N-methyl-(Z)-2-[2-(5-fluoro-2'-methyl-3'-chlorophenoxy-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide

Guidance literature:: 3-chloro-o-cresol; With potassium carbonate; In acetonitrile; at 20 ℃; for 0.5h;

N-methyl-(Z)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide; N-methyl-(E)-2-[2-(5,6-difluoro-pyrimidin-4-yloxy)-phenyl]-2-methoxyiminoacetamide; at 0 - 20 ℃; for 12h;