3260-87-5

Basic information

• Product Name: 3-CHLORO-2-METHYLPHENOL
• Synonyms: 3-CHLORO-2-METHYLPHENOL;3-chloro-o-cresol;3-Chloro-2-methylphenol 98%;2-Chloro-6-hydroxytoluene, 3-Chloro-o-cresol
• CAS NO: 3260-87-5
• Molecular Formula: C₇H₇ClO
• Molecular Weight: 142.58
• EINECS: 221-861-0
• Product Categories: Phenol&Thiophenol&Mercaptan;Chlorine Compounds;Phenols;Pesticide Intermediate
• Mol File: 3260-87-5.mol
• Article Data: 17

Chemical Properties

• Melting Point: 86 °C
• Boiling Point: 225 °C
• Flash Point: 84.8 °C
• Appearance: /
• Density: 1.1104 (rough estimate)
• Vapor Pressure: 0.0592mmHg at 25°C
• Refractive Index: 1.5449 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 9.35±0.10(Predicted)
• Sensitive: Stench
• CAS DataBase Reference: 3-CHLORO-2-METHYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-2-METHYLPHENOL(3260-87-5)
• EPA Substance Registry System: 3-CHLORO-2-METHYLPHENOL(3260-87-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 21/22-41-43-50-38-36
• Safety Statements: 26-36/37/39-28
• RIDADR: 3437
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 3260-87-5(Hazardous Substances Data)

Usage

General Description

3-Chloro-2-methylphenol is a chemical compound with the molecular formula C7H7ClO. It is a white crystalline solid with a slight phenolic odor, and it is soluble in organic solvents. This chemical is commonly used as a disinfectant and antiseptic in various industrial and household products, including soaps, personal care products, and medical disinfectants. 3-Chloro-2-methylphenol is also utilized in the preservation of paints, coatings, and adhesives. However, it is important to handle this substance with care, as it can be harmful if ingested or inhaled in large quantities, and it may cause skin and eye irritation upon contact.

InChI:InChI=1/C7H7ClO/c1-5-6(8)3-2-4-7(5)9/h2-4,9H,1H3

Upstream product

• 95-49-8 2-methylchlorobenzene 
• 118-69-4 2,6-dichlorotoluene 
• 80-73-9 1,3-dimethyl-2-imidazolidinone 
• 3260-88-6 1-chloro-3-methoxy-2-methylbenzene 
• 83-42-1 6-chloro-2-nitrotoluene 
• 87-60-5 3-chloro-2-methylbenzenamine 

Downstream Products

• 55289-28-6 3-chloro-2-methyl-4-nitro-phenol 
• 83577-91-7 3-chloro-2-methyl-6-nitro-phenol 
• 55289-27-5 3-chloro-2-methyl-4,6-dinitro-phenol 
• 3260-88-6 1-chloro-3-methoxy-2-methylbenzene 
• 60963-08-8 1,3-Dichloro-2-(3-chloro-2-methyl-phenoxy)-5-nitro-benzene 
• 1125-75-3 3-Chlor-2-methyl-phenylcyanat 
• 361377-28-8 4-chloro-6-(3-chloro-2-methylphenoxy)-5-fluoropyrimidine 
• 608-25-3 2-methylbenzene-1,3-diol 
• 1243545-24-5 3-chloro-2-methyl-6-(2-methylallyl)phenol 
• 60962-80-3 1-[3,5-Dichloro-4-(3-chloro-2-methyl-phenoxy)-phenyl]-3-((E)-3-ethoxy-acryloyl)-urea 
• 60963-36-2 3,5-Dichloro-4-(3-chloro-2-methyl-phenoxy)-phenylamine 
• 3260-89-7 2-chloro-6-methoxybenzoic acid 
• 6563-60-6 methoxy-9H-xanthen-9-one 
• 38169-98-1 5-Chlor-2H-1-benzopyran-2-on 

Relevant articles and documents

Method for synthesizing 3 - halogen -2 -alkyl phenol

The invention discloses a synthesis method of 3 -halo -2 - alkyl phenol, and belongs to the technical field of organic synthesis. At 2, 6 - dihaloalkylbenzene is used as starting material, nucleophilic substitution with dibenzyl alcohol in the presence of an inorganic base followed Pd / C hydrodebenzylation or Grignard exchange with magnesium metal in the presence of n-butylbromide/chloride followed by air/oxygen to give 3 - halo -2 - alkylphenols. The method has the advantages of high regioselectivity, good yield, simple operation process and the like, and the product purity can reach 99.5% or more.

Method for synthesizing 2,6-dihydroxytoluene by using waste acid

The invention discloses a method for synthesizing 2,6-dihydroxytoluene by using waste acid mechanically. According to the method, 3-chloro-2-methylaniline is taken as a raw material, an intermediate 3-chloro-2-methylphenol is synthesized through diazotization and hydrolysis, the reaction is optimized in the alkali fusion, acidification and refining processes, the mechanical application of waste acid and a solvent in the reaction and the optimization of a refining scheme are emphatically optimized, the yield is effectively improved, three wastes are reduced, and 2,6-dihydroxytoluene is synthesized. The method provided by the invention greatly reduces the generation of acidic wastewater, better meets the requirement of environmental protection, and effectively increases the yield of the product, and the quality of the product reaches 99.0-99.5%.

Process for the preparation of phenols

The present invention relates to a process for the preparation of phenols in which an aryldiazonium salt, which is prepared by the diazotization of a corresponding aromatic, primary amine, by heating in a mixture comprising hot water, a mineral acid and an organic solvent, is decomposed, where the organic solvent comprises a ketone of the formula (I) R1C(O)R2, in which R1 and R2, independently of one another, are (C1-C5)-alkyl and R1 and R2 together have at least four carbon atoms, where the aromatic primary amine is aniline or a substituted aniline which comprises at least one further substituent which is selected from: alkyl, alkenyl, alkynyl, halogen, haloalkyl, cycloalkyl, heteroalkyl, carboxyl, cyano, alkoxy and ester, and where essentially no copper salts are present in the mixture.