methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside

Base Information

• Chemical Name: methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside
• CAS No.: 683773-18-4
• Molecular Formula: C₁₇H₂₃ClO₅S
• Molecular Weight: 374.886

Synonyms:methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside

Chemical Property of methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside

There total 3 articles about methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Chloroacetic anhydride (541-88-8) + methyl 3-O-benzyl-2-O-methyl-1-thio-β-L-fucopyranoside (683773-17-3) → methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside (683773-18-4)

Guidance literature:

With pyridine; In dichloromethane; at -15 - 0 ℃; for 1h;

DOI:10.1021/jo030304e

Reference yield:

benzyl bromide (100-39-0) → methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside (683773-18-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Bu₂SnO / benzene / 24 h / Heating

1.2: 65 percent / CsF / dimethylformamide / 48 h / 20 °C

2.1: 91 percent / pyridine / CH₂Cl₂ / 1 h / -15 - 0 °C

With pyridine; di(n-butyl)tin oxide; In dichloromethane; benzene;

DOI:10.1021/jo030304e

Reference yield:

Methyl 2-O-methyl-1-thio-β-L-fucopyranoside (151669-17-9) → methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside (683773-18-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Bu₂SnO / benzene / 24 h / Heating

1.2: 65 percent / CsF / dimethylformamide / 48 h / 20 °C

2.1: 91 percent / pyridine / CH₂Cl₂ / 1 h / -15 - 0 °C

With pyridine; di(n-butyl)tin oxide; In dichloromethane; benzene;

DOI:10.1021/jo030304e

upstream raw materials:

Chloroacetic anhydride

methyl 3-O-benzyl-2-O-methyl-1-thio-β-L-fucopyranoside

benzyl bromide

Methyl 2-O-methyl-1-thio-β-L-fucopyranoside

Downstream raw materials:

4-pentenyl 2,4-di-O-benzyl-3-O-[3-O-benzyl-2-O-methyl-4-O-(2,3-di-O-benzyl-4-O-methyl-α-L-rhamnopyranosyl)-α-L-fucopyranosyl]-α-L-rhamnopyranoside

4-pentenyl 2,4-di-O-acetyl-3-O-[3-O-benzyl-2-O-methyl-4-O-(2,3-di-O-acetyl-4-O-methyl-α-L-rhamnopyranosyl)-α-L-fucopyranosyl]-α-L-rhamnopyranoside

4-pentenyl 2,4-di-O-acetyl-3-O-(3-O-benzyl-2-O-methyl-α-L-fucopyranosyl)-α-L-rhamnopyranoside

4-pentenyl 2,4-di-O-acetyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-α-L-rhamnopyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 683773-18-4 methyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send