Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Base Information

Chemical Name:Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester
CAS No.:251353-63-6
Molecular Formula:C₅₃H₆₈O₈
Molecular Weight:833.118
Hs Code.:

Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Synonyms:Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Suppliers and Price of Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

There total 17 articles about Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 251353-62-5
Formic acid (6R,7S,9S)-6,7,9-tris-benzyloxy-1-((1R,3S,4R,5R)-4-benzyloxy-3-formyloxy-1,5-dimethyl-heptyl)-10-(tetrahydro-pyran-2-yloxy)-dec-2-ynyl ester

: 251353-63-6
Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Guidance literature:: With palladium diacetate; tributylphosphine; In tetrahydrofuran;
DOI:10.1016/S0040-4039(99)01322-2

Reference yield:

: (2S,3R)-3-Benzyloxy-2-methyl-3-((S)-5-oxo-tetrahydro-furan-2-yl)-propionaldehyde

: 251353-63-6
Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: n-BuLi / tetrahydrofuran

2: H₂ / Pd-C / ethyl acetate

3: TfOH / CH₂Cl₂; cyclohexane

4: 68 percent / LiHMDS / tetrahydrofuran / -78 °C

5: 72 percent / n-BuLi / diethyl ether / -20 °C

6: 85 percent / NaBH₄; CeCl₃ / methanol

7: 97 percent / Ac₂O; Py

8: 84 percent / Pd(OAc)2; n-Bu₃P / tetrahydrofuran

With pyridine; palladium diacetate; sodium tetrahydroborate; n-butyllithium; cerium(III) chloride; tributylphosphine; trifluorormethanesulfonic acid; hydrogen; acetic anhydride; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; cyclohexane; ethyl acetate; 1: Condensation / 2: Catalytic hydrogenation / 3: Etherification / 4: Alkylation / 5: Acylation / 6: Reduction / 7: Esterification / 8: deoxygenation;
DOI:10.1016/S0040-4039(99)01322-2

Reference yield:

: 251353-58-9
(S)-5-((1R,2R)-1-Benzyloxy-2-methyl-but-3-enyl)-dihydro-furan-2-one

: 251353-63-6
Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: H₂ / Pd-C / ethyl acetate

2: TfOH / CH₂Cl₂; cyclohexane

3: 68 percent / LiHMDS / tetrahydrofuran / -78 °C

4: 72 percent / n-BuLi / diethyl ether / -20 °C

5: 85 percent / NaBH₄; CeCl₃ / methanol

6: 97 percent / Ac₂O; Py

7: 84 percent / Pd(OAc)2; n-Bu₃P / tetrahydrofuran

With pyridine; palladium diacetate; sodium tetrahydroborate; n-butyllithium; cerium(III) chloride; tributylphosphine; trifluorormethanesulfonic acid; hydrogen; acetic anhydride; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; cyclohexane; ethyl acetate; 1: Catalytic hydrogenation / 2: Etherification / 3: Alkylation / 4: Acylation / 5: Reduction / 6: Esterification / 7: deoxygenation;
DOI:10.1016/S0040-4039(99)01322-2