benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodec-8-yl ester

Base Information

• Chemical Name: benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodec-8-yl ester
• CAS No.: 925545-55-7
• Molecular Formula: C₃₁H₃₃NO₆
• Molecular Weight: 515.606

Synonyms:benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodec-8-yl ester

Chemical Property of benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodec-8-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodec-8-yl ester

There total 10 articles about benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodec-8-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C31H33NO6 → benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.03,7]dodec-8-yl ester (925545-55-7)

Guidance literature:

With triethylamine; In acetonitrile; for 2h; Heating;

DOI:10.1021/ol062621o

Reference yield:

1-(2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-prop-2-en-1-ol (881302-89-2) → benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.03,7]dodec-8-yl ester (925545-55-7)

Guidance literature:

Multi-step reaction with 8 steps

1: pyridine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 °C

2: 535 mg / AcOH / H₂O / 11 h / 20 °C

3: imidazole / CH₂Cl₂ / 2 h / 20 °C

4: trifluoromethanesulfonic acid / cyclohexane; CH₂Cl₂ / 3.5 h / 0 - 20 °C

5: 324 mg / TBAF / tetrahydrofuran / 3 h / 20 °C

6: IBX / dimethylsulfoxide; CH₂Cl₂ / 12 h / 20 °C

7: CH₂Cl₂ / 1 h / 20 °C

8: 83.1 mg / triethylamine / acetonitrile / 2 h / Heating

With pyridine; 1H-imidazole; dmap; trifluorormethanesulfonic acid; tetrabutyl ammonium fluoride; acetic acid; triethylamine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dichloromethane; cyclohexane; water; dimethyl sulfoxide; acetonitrile;

DOI:10.1021/ol062621o

Reference yield:

benzoic acid 1-[5-(1,2-dihydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester (925545-45-5) → benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.03,7]dodec-8-yl ester (925545-55-7)

Guidance literature:

Multi-step reaction with 6 steps

1: imidazole / CH₂Cl₂ / 2 h / 20 °C

2: trifluoromethanesulfonic acid / cyclohexane; CH₂Cl₂ / 3.5 h / 0 - 20 °C

3: 324 mg / TBAF / tetrahydrofuran / 3 h / 20 °C

4: IBX / dimethylsulfoxide; CH₂Cl₂ / 12 h / 20 °C

5: CH₂Cl₂ / 1 h / 20 °C

6: 83.1 mg / triethylamine / acetonitrile / 2 h / Heating

With 1H-imidazole; trifluorormethanesulfonic acid; tetrabutyl ammonium fluoride; triethylamine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dichloromethane; cyclohexane; dimethyl sulfoxide; acetonitrile;

DOI:10.1021/ol062621o

upstream raw materials:

1-(2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-prop-2-en-1-ol

benzoic acid 1-[5-(1,2-dihydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

benzoic acid 1-[5-(1-benzyloxy-2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

benzoic acid 1-{5-[2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-allyl ester

Downstream raw materials:

11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodecan-8-one

11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodecan-8-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 925545-55-7 benzoic acid 11-benzyl-2-benzyloxy-5,5-dimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodec-8-yl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send