C₆₀H₉₂N₄O₁₂S

Base Information

• Chemical Name: C₆₀H₉₂N₄O₁₂S
• CAS No.: 905846-86-8
• Molecular Formula: C₆₀H₉₂N₄O₁₂S
• Molecular Weight: 1093.48
• Mol file: 905846-86-8.mol

Synonyms:C₆₀H₉₂N₄O₁₂S

Chemical Property of C₆₀H₉₂N₄O₁₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₀H₉₂N₄O₁₂S

There total 3 articles about C₆₀H₉₂N₄O₁₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

9-deoxo-9a-aza-9a-demethyl-9a-(3-aminopropyl)-9a-homoerythromycin A (92594-46-2) + trityl isothiocyanate (1726-94-9) → C60H92N4O12S (905846-86-8)

Guidance literature:

In dichloromethane; at 20 ℃; for 48h; Combinatorial reaction / High throughput screening (HTS);

DOI:10.1016/j.bmc.2011.01.030

Reference yield:

9-deoxo-9a-aza-9a-(β-cyanoethyl)-9a-homoerythromycin A (92627-70-8) → C60H92N4O12S (905846-86-8)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum(IV) oxide; hydrogen; acetic acid / 12 h / 3750.38 Torr

2: dichloromethane / 48 h / 20 °C / Combinatorial reaction / High throughput screening (HTS)

With platinum(IV) oxide; hydrogen; acetic acid; In dichloromethane;

DOI:10.1016/j.bmc.2011.01.030

Reference yield:

9-Deoxo-9a-aza-9a-homoerythromycin A (76801-85-9) → C60H92N4O12S (905846-86-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 24 h / 80 °C

2: platinum(IV) oxide; hydrogen; acetic acid / 12 h / 3750.38 Torr

3: dichloromethane / 48 h / 20 °C / Combinatorial reaction / High throughput screening (HTS)

With platinum(IV) oxide; hydrogen; acetic acid; In dichloromethane; 1: Michael addition;

DOI:10.1016/j.bmc.2011.01.030

upstream raw materials:

9-deoxo-9a-aza-9a-(β-cyanoethyl)-9a-homoerythromycin A

9-deoxo-9a-aza-9a-demethyl-9a-(3-aminopropyl)-9a-homoerythromycin A

trityl isothiocyanate

9-Deoxo-9a-aza-9a-homoerythromycin A

Refernces