Technology Process of 2-Benzofurancarboxylicacid,6-amino-5-hydroxy-,methylester(9CI)
There total 6 articles about 2-Benzofurancarboxylicacid,6-amino-5-hydroxy-,methylester(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran;
for 23h;
DOI:10.1002/hlca.19940770113
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 43 percent / K2CO3 / dimethylformamide / 4 h, r.t.; 18 h, 80 deg C
2: 26 percent / BBr3 / CH2Cl2 / 18 h
3: 90 percent / SO2Cl2 / CH2Cl2 / 3 h
4: 66 percent / 96percent H2SO4, 100percent HNO3 / 2.5 h / 0 °C
5: 99 percent / H2, triethylamine / 5percent Pd/C / tetrahydrofuran / 23 h
With
sulfuryl dichloride; sulfuric acid; hydrogen; nitric acid; boron tribromide; potassium carbonate; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/hlca.19940770113
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 26 percent / BBr3 / CH2Cl2 / 18 h
2: 90 percent / SO2Cl2 / CH2Cl2 / 3 h
3: 66 percent / 96percent H2SO4, 100percent HNO3 / 2.5 h / 0 °C
4: 99 percent / H2, triethylamine / 5percent Pd/C / tetrahydrofuran / 23 h
With
sulfuryl dichloride; sulfuric acid; hydrogen; nitric acid; boron tribromide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/hlca.19940770113
