Methyl 5-hydroxybenzofuran-2-carboxylate

Base Information

Chemical Name:Methyl 5-hydroxybenzofuran-2-carboxylate
CAS No.:1646-28-2
Molecular Formula:C₁₀H₈O₄
Molecular Weight:192.171
Hs Code.:2932999099
DSSTox Substance ID:DTXSID40480529
Nikkaji Number:J2.251.489J
Wikidata:Q82315351
Mol file:1646-28-2.mol

Synonyms:1646-28-2;Methyl 5-hydroxybenzofuran-2-carboxylate;Methyl 5-hydroxy-1-benzofuran-2-carboxylate;2-Benzofurancarboxylic acid, 5-hydroxy-, methyl ester;5-Hydroxy-benzofuran-2-carboxylic acid methyl ester;5-Hydroxy-2-benzofurancarboxylic acid methyl ester;5-hydroxybenzofuran-2-carboxylic acid methyl ester;SCHEMBL445684;DTXSID40480529;KPSJSEXMKPMEAM-UHFFFAOYSA-N;2-carbomethoxy-5-hydroxy-benzofuran;BAA64628;MFCD13192384;AKOS022183757;Methyl5-hydroxybenzofuran-2-carboxylate;AS-53607;P16754

Suppliers and Price of Methyl 5-hydroxybenzofuran-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 7 raw suppliers

Chemical Property of Methyl 5-hydroxybenzofuran-2-carboxylate

Chemical Property:

Melting Point:168-169 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling Point:326.2±22.0 °C(Predicted)
PKA:8.89±0.40(Predicted)
PSA：59.67000
Density:1.346±0.06 g/cm3(Predicted)
LogP:1.92500
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:192.04225873
Heavy Atom Count:14
Complexity:228

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC2=C(O1)C=CC(=C2)O

Technology Process of Methyl 5-hydroxybenzofuran-2-carboxylate

There total 11 articles about Methyl 5-hydroxybenzofuran-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 56172-36-2
5-Hydroxybenzofuran-2-carboxylic acid

: 1646-28-2
5-hydroxy-benzofuran-2-carboxylic acid methyl ester

Guidance literature:: With PS 4-(methylazoamino)phenoxymethyl resin; In dichloromethane; at 20 ℃; for 2h;

Reference yield: 94.0%

: 1751-24-2
5-methoxy-benzofuran-2-carboxylic acid methyl ester

: 1646-28-2
5-hydroxy-benzofuran-2-carboxylic acid methyl ester

Guidance literature:: 5-methoxy-benzofuran-2-carboxylic acid methyl ester; With boron tribromide; In dichloromethane; at -40 - 20 ℃;

With methanol; In dichloromethane;

With thionyl chloride; water; more than 3 stages;