1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

Base Information

Chemical Name:1α-di<(2-methoxyethoxy)methoxy>vitamin D₃
CAS No.:162889-26-1
Molecular Formula:C₃₅H₆₀O₆
Molecular Weight:576.858
Hs Code.:

1α-di<(2-methoxyethoxy)methoxy>vitamin D<sub>3</sub>

Synonyms:1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

Suppliers and Price of 1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

There total 14 articles about 1α-di<(2-methoxyethoxy)methoxy>vitamin D₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 93490-17-6
(8E)-8-bromomethylene-de-A,B-cholestane

: 162889-20-5
(4R,6S)-4,6-bis[(2-methoxyethoxyethyl)oxy]-7-octen-1-yne

: 162889-26-1
1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex;
DOI:10.1016/0040-4039(94)02209-T

Reference yield:

: 87-72-9,608-45-7,608-46-8,608-47-9,2460-44-8,6748-95-4,6763-34-4,7261-26-9,7283-06-9,7283-07-0,7296-55-1,7296-56-2,7296-58-4,7296-59-5,7296-60-8,7296-61-9,7296-62-0,7322-30-7,10257-31-5,10257-32-6,10257-33-7,10257-34-8,10257-35-9,19982-83-3,20242-88-0,28697-53-2,36562-42-2,41546-41-2,89299-64-9,107655-34-5,115794-06-4,115794-07-5,130550-15-1,130606-21-2
D-Xylose

: 162889-26-1
1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

Guidance literature:: Multi-step reaction with 14 steps

1: Br₂, K₂CO₃ / H₂O / Ambient temperature

2: acetic acid / 50 °C

3: 97 percent / H₂, Et₃N / Pd/C / ethyl acetate / Ambient temperature

4: 90 percent / KOH, H₂O / ethanol / Ambient temperature

5: 95 percent / imidazole / dimethylformamide / Ambient temperature

6: 97 percent / (iPr)2NEt / CH₂Cl₂ / Ambient temperature

7: 97 percent / DIBAL / CH₂Cl₂ / -65 °C

8: 65 percent / tBuOK / tetrahydrofuran / 0 °C

9: 97 percent / (nBu)4NF / tetrahydrofuran / Ambient temperature

10: 74 percent / pyridine / -5 °C

11: 95 percent / K₂CO₃ / ethanol / Ambient temperature

12: 95 percent / dimethylsulfoxide / Ambient temperature

13: 97 percent / (iPr)2NEt / CH₂Cl₂ / Ambient temperature

14: 51 percent / (dba)3Pd₂*CHCl₃

With pyridine; 1H-imidazole; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium hydroxide; potassium tert-butylate; tetrabutyl ammonium fluoride; water; hydrogen; bromine; diisobutylaluminium hydride; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; water; acetic acid; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(94)02209-T

Reference yield:

D-xylono-1,5-lactone: 82796-87-0
D-xylono-1,5-lactone

: 162889-26-1
1α-di<(2-methoxyethoxy)methoxy>vitamin D₃

Guidance literature:: Multi-step reaction with 13 steps

1: acetic acid / 50 °C

2: 97 percent / H₂, Et₃N / Pd/C / ethyl acetate / Ambient temperature

3: 90 percent / KOH, H₂O / ethanol / Ambient temperature

4: 95 percent / imidazole / dimethylformamide / Ambient temperature

5: 97 percent / (iPr)2NEt / CH₂Cl₂ / Ambient temperature

6: 97 percent / DIBAL / CH₂Cl₂ / -65 °C

7: 65 percent / tBuOK / tetrahydrofuran / 0 °C

8: 97 percent / (nBu)4NF / tetrahydrofuran / Ambient temperature

9: 74 percent / pyridine / -5 °C

10: 95 percent / K₂CO₃ / ethanol / Ambient temperature

11: 95 percent / dimethylsulfoxide / Ambient temperature

12: 97 percent / (iPr)2NEt / CH₂Cl₂ / Ambient temperature

13: 51 percent / (dba)3Pd₂*CHCl₃

With pyridine; 1H-imidazole; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium hydroxide; potassium tert-butylate; tetrabutyl ammonium fluoride; water; hydrogen; diisobutylaluminium hydride; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; acetic acid; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(94)02209-T