1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

Base Information

Chemical Name:1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine
CAS No.:101544-41-6
Molecular Formula:C₂₈H₃₁N₃O₃
Molecular Weight:457.572
Hs Code.:

1-acetyl-5-<1-(acetyloxy)-2-<bis(phenylmethyl)amino>ethyl>-2,3-dihydro-1H-indole-7-amine

Synonyms:1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

Suppliers and Price of 1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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price

Total 1 raw suppliers

Chemical Property of 1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of 1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

There total 6 articles about 1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 101629-42-9
1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

: 101544-41-6
1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

Guidance literature:: With acetic acid; zinc; In ethanol; for 0.5h; Ambient temperature;
DOI:10.1021/jm00156a019

Reference yield:

: 16078-30-1
1-Acetyl-2,3-dihydro-1H-indole

: 101544-41-6
1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) aluminum chloride / 1.) 1,2-dichloroethane, 20 min, 2.) 1,2-dichloroethane, 50 deg C, 1 h

2: dimethylformamide / 2 h / 60 °C

3: NaBH₄ / ethanol / 1.) RT, 4.5 h, 2.) 50 deg C, 1 h

4: 94.5 percent / pyridine / Ambient temperature

5: 85.9 percent / 90percent nitric acid / acetic acid / 6 h / Ambient temperature

6: 93 percent / acetic acid, zinc dust / ethanol / 0.5 h / Ambient temperature

With pyridine; sodium tetrahydroborate; aluminium trichloride; nitric acid; acetic acid; zinc; In ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00156a019

Reference yield:

: 76139-03-2
2-chloro-1-(1-acetyl-2,3-dihydroindole-5-yl)ethanone

: 101544-41-6
1-acetyl-5-<1-(acetyloxy)-2-ethyl>-2,3-dihydro-1H-indole-7-amine

Guidance literature:: Multi-step reaction with 5 steps

1: dimethylformamide / 2 h / 60 °C

2: NaBH₄ / ethanol / 1.) RT, 4.5 h, 2.) 50 deg C, 1 h

3: 94.5 percent / pyridine / Ambient temperature

4: 85.9 percent / 90percent nitric acid / acetic acid / 6 h / Ambient temperature

5: 93 percent / acetic acid, zinc dust / ethanol / 0.5 h / Ambient temperature

With pyridine; sodium tetrahydroborate; nitric acid; acetic acid; zinc; In ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00156a019