N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine

Base Information

Chemical Name:N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine
CAS No.:120075-66-3
Molecular Formula:C₂₁H₂₆N₄O₂
Molecular Weight:366.463
Hs Code.:

Synonyms:N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:: SDS file from LookChem

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Technology Process of N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine

There total 1 articles about N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 120075-53-8
5-(benzyloxy)-4-chloro-6-methoxyquinazoline

: 109-55-7
1-amino-3-(dimethylamino)propane

: 120075-66-3
N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine

Guidance literature:: With triethylamine; In ethanol; for 24h; Ambient temperature;
DOI:10.1021/jm00105a007

Reference yield:

: 120075-66-3
N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine

: 120075-43-6
6,7-Bis-aziridin-1-yl-4-(3-dimethylamino-propylamino)-quinazoline-5,8-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / H₂ / 10percent Pd/C / dioxane; methanol / 760 Torr / Ambient temperature

2: 51 percent / KH₂PO₄, (KSO₃)2NO / methanol; H₂O / 4 h

3: 35 percent / 4.5 h / 0 °C

With potassium dihydrogenphosphate; potassium nitrososulfonate; hydrogen; palladium on activated charcoal; In 1,4-dioxane; methanol; water;
DOI:10.1021/jm00105a007

Reference yield:

: 120075-66-3
N'-(5-Benzyloxy-6-methoxy-quinazolin-4-yl)-N,N-dimethyl-propane-1,3-diamine

: 120075-57-2
4-(3-Dimethylamino-propylamino)-6-methoxy-quinazoline-5,8-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / H₂ / 10percent Pd/C / dioxane; methanol / 760 Torr / Ambient temperature

2: 51 percent / KH₂PO₄, (KSO₃)2NO / methanol; H₂O / 4 h

With potassium dihydrogenphosphate; potassium nitrososulfonate; hydrogen; palladium on activated charcoal; In 1,4-dioxane; methanol; water;
DOI:10.1021/jm00105a007