5-bromo-N-(4-chlorophenyl)-2-fluorobenzamide

Base Information

Chemical Name:5-bromo-N-(4-chlorophenyl)-2-fluorobenzamide
CAS No.:853317-08-5
Molecular Formula:C₁₃H₈BrClFNO
Molecular Weight:328.568
Hs Code.:
European Community (EC) Number:662-482-4
Mol file:853317-08-5.mol

Synonyms:5-bromo-N-(4-chlorophenyl)-2-fluorobenzamide;AKOS000183516

Suppliers and Price of 5-bromo-N-(4-chlorophenyl)-2-fluorobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5-BROMO-N-(4-CHLOROPHENYL)-2-FLUOROBENZAMIDE Aldrich
100mg
$ 57.00

American Custom Chemicals Corporation
5-BROMO-N-(4-CHLOROPHENYL)-2-FLUOROBENZAMIDE 95.00%
5MG
$ 499.53

Total 1 raw suppliers

Chemical Property of 5-bromo-N-(4-chlorophenyl)-2-fluorobenzamide

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:326.94618
Heavy Atom Count:18
Complexity:297

Purity/Quality:: 5-BROMO-N-(4-CHLOROPHENYL)-2-FLUOROBENZAMIDE Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)C2=C(C=CC(=C2)Br)F)Cl

Technology Process of 5-bromo-N-(4-chlorophenyl)-2-fluorobenzamide

There total 1 articles about 5-bromo-N-(4-chlorophenyl)-2-fluorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 214210-17-0
5-bromo-2-fluorobenzamide

: 637-87-6
1-Chloro-4-iodobenzene

: 853317-08-5
C₁₃H₈BrClFNO

Guidance literature:: With copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.05.127

Reference yield: 92.0%

: 557-21-1
zinc(II) cyanide

: 853317-08-5
C₁₃H₈BrClFNO

: 1325219-50-8
C₁₄H₈ClFN₂O

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; zinc; In N,N-dimethyl acetamide; at 100 ℃; for 12h;
DOI:10.1016/j.bmcl.2011.05.127

Reference yield:

: 853317-08-5
C₁₃H₈BrClFNO

: 1325219-52-0
C₁₅H₁₁ClN₂OS

Guidance literature:: Multi-step reaction with 2 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 1,1'-bis-(diphenylphosphino)ferrocene; zinc / N,N-dimethyl acetamide / 12 h / 100 °C

2: dimethyl sulfoxide

With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; zinc; In N,N-dimethyl acetamide; dimethyl sulfoxide;
DOI:10.1016/j.bmcl.2011.05.127