2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole

Base Information

• Chemical Name: 2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole
• CAS No.: 1216874-68-8
• Molecular Formula: C₂₁H₁₆Cl₂N₂
• Molecular Weight: 367.277
• Mol file: 1216874-68-8.mol

Synonyms:2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole

Chemical Property of 2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole

There total 2 articles about 2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-chloro-benzaldehyde (89-98-5) + 3-methyl-1,2-benzenediamine (2687-25-4) → 2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole (1216874-68-8)

Guidance literature:

With silica supported P₂O₅; at 20 ℃; for 0.133333h; neat (no solvent);

DOI:10.1002/cjoc.201180408

Reference yield:

2-chloro-benzaldehyde (89-98-5) + 3-methyl-1,2-benzenediamine (2687-25-4) → 2-(2-chlorophenyl)-1-(2-chlorophenylmethyl)-4-methyl-1H-benzimidazole (1216874-68-8) + C21H16Cl2N2

Guidance literature:

With iron(III)sulfate-silica; at 30 ℃; for 5h; Neat (no solvent);

DOI:10.1016/j.tetlet.2012.05.129

upstream raw materials:

2-chloro-benzaldehyde

3-methyl-1,2-benzenediamine