Welcome to LookChem.com Sign In|Join Free

CAS

  • or

2687-25-4

Post Buying Request

2687-25-4 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

2687-25-4 Usage

Chemical Properties

brown powder

Uses

Inducer of CYP1A activity, and possible mutagenic carcinogen.

General Description

The antitumour activity of Pd(II) and Pt(II) new complexes with 2,3-diaminotoluene was studied. 2,3-Diaminotoluene induced CYP1A activity.

Check Digit Verification of cas no

The CAS Registry Mumber 2687-25-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,8 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2687-25:
(6*2)+(5*6)+(4*8)+(3*7)+(2*2)+(1*5)=104
104 % 10 = 4
So 2687-25-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2/c1-5-3-2-4-6(8)7(5)9/h2-4H,8-9H2,1H3

2687-25-4 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A15647)  2,3-Diaminotoluene, 97%   

  • 2687-25-4

  • 5g

  • 802.0CNY

  • Detail
  • Alfa Aesar

  • (A15647)  2,3-Diaminotoluene, 97%   

  • 2687-25-4

  • 25g

  • 3409.0CNY

  • Detail
  • Alfa Aesar

  • (A15647)  2,3-Diaminotoluene, 97%   

  • 2687-25-4

  • 100g

  • 11593.0CNY

  • Detail
  • Aldrich

  • (272361)  2,3-Diaminotoluene  97%

  • 2687-25-4

  • 272361-5G

  • 961.74CNY

  • Detail

2687-25-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-DIAMINOTOLUENE

1.2 Other means of identification

Product number -
Other names 1,2-diamino-3-methylbenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2687-25-4 SDS

2687-25-4Relevant articles and documents

Synthesis and Antifungal Activity of Substituted 2-Aryl Benzimidazoles Derivatives

Huang, Daye,Qiu, Fang,Zhang, Zhigang,Shi, Liqiao,Cao, Chunxia,Ke, Shaoyong

, p. 2494 - 2498 (2019)

Benzimidazole fungicides were among the early systemic fungicides developed and used for controlling a wide variety of plant diseases. During the course of our screening process for active compounds, two 2-aryl benzimidazoles derivatives bearing sulfoxide group (6b and 6c) have been demonstrated to exhibit good inhibition activity against high-resistant isolate of Botrytis cinerea compared with carbendazim, and the inhibition rates are up to 46.67% and 51.11% at the concentration of 10 μg/mL, which might be considered as the active framework for the discovery of novel fungicide to high-resistant isolate of B. cinerea.

Metabolism of 1H-benzotriazolecarboxylic acids in vitro and in vivo

Hoffmann,Jacobi

, p. 457 - 459 (1989)

-

Regioselective Radical Arene Amination for the Concise Synthesis ofortho-Phenylenediamines

Gillespie, James E.,Morrill, Charlotte,Phipps, Robert J.

supporting information, p. 9355 - 9360 (2021/07/19)

The formation of arene C-N bonds directly from C-H bonds is of great importance and there has been rapid recent development of methods for achieving this through radical mechanisms, often involving reactiveN-centered radicals. A major challenge associated with these advances is that of regiocontrol, with mixtures of regioisomeric products obtained in most protocols, limiting broader utility. We have designed a system that utilizes attractive noncovalent interactions between an anionic substrate and an incoming radical cation in order to guide the latter to the areneorthoposition. The anionic substrate takes the form of a sulfamate-protected aniline and telescoped cleavage of the sulfamate group after amination leads directly toortho-phenylenediamines, key building blocks for a range of medicinally relevant diazoles. Our method can deliver both free amines and monoalkyl amines allowing access to unsymmetrical, selectively monoalkylated benzimidazoles and benzotriazoles. As well as providing concise access to valuableortho-phenylenediamines, this work demonstrates the potential for utilizing noncovalent interactions to control positional selectivity in radical reactions.

2-Aminopyrimidine Derivatives as New Selective Fibroblast Growth Factor Receptor 4 (FGFR4) Inhibitors

Mo, Cheng,Zhang, Zhang,Guise, Christopher P.,Li, Xueqiang,Luo, Jinfeng,Tu, Zhengchao,Xu, Yong,Patterson, Adam V.,Smaill, Jeff B.,Ren, Xiaomei,Lu, Xiaoyun,Ding, Ke

supporting information, p. 543 - 548 (2017/05/19)

A series of 2-aminopyrimidine derivatives were designed and synthesized as highly selective FGFR4 inhibitors. One of the most promising compounds 2n tightly bound FGFR4 with a Kd value of 3.3 nM and potently inhibited its enzymatic activity with an IC50 value of 2.6 nM, but completely spared FGFR1/2/3. The compound selectively suppressed proliferation of breast cancer cells harboring dysregulated FGFR4 signaling with an IC50 value of 0.38 μM. Furthermore, 2n exhibited extraordinary target specificity in a Kinome-wide screen against 468 kinases, with S(35) and S(10) selectivity scores of 0.01 and 0.007 at 1.0 μM, respectively.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 2687-25-4