2-phenyl-4-hexenenitrile

Base Information

• Chemical Name: 2-phenyl-4-hexenenitrile
• CAS No.: 54929-98-5
• Molecular Formula: C₁₂H₁₃N
• Molecular Weight: 171.242
• Mol file: 54929-98-5.mol

Synonyms:2-phenyl-4-hexenenitrile

Chemical Property of 2-phenyl-4-hexenenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-phenyl-4-hexenenitrile

There total 3 articles about 2-phenyl-4-hexenenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

nitrostyrene (5153-67-3) + (1-methyl-2-propenyl)dimethylphenylsilane (35802-48-3) → 2-phenyl-4-hexenenitrile (54929-98-5) + phenylacetonitrile (140-29-4) + 2-phenyl-4-hexenenitrile

Guidance literature:

With titanium tetrachloride; zinc; In tetrahydrofuran; dichloromethane; at -15 ℃; for 3h; Yields of byproduct given;

DOI:10.1246/bcsj.59.1267

Reference yield:

bromo-phenyl-acetonitrile (5798-79-8) → 2-phenyl-4-hexenenitrile (54929-98-5) + 3-Methyl-2-phenyl-4-pentenenitrile (106046-53-1)

Guidance literature:

In dichloromethane; for 2h; Yield given. Yields of byproduct given; Ambient temperature;

DOI:10.1016/S0040-4020(01)97186-8

Reference yield:

phenylacetonitrile (140-29-4) + buta-1,3-diene (106-99-0,130983-70-9,29406-96-0,9003-17-2) → 2-phenyl-4-hexenenitrile (54929-98-5)

Guidance literature:

With bis(acetylacetonate)nickel(II); sodium tetrahydroborate; di(isopropyl) phenylphosphonite;

DOI:10.1016/S0022-328X(00)89791-0

upstream raw materials:

phenylacetonitrile

buta-1,3-diene

nitrostyrene

(1-methyl-2-propenyl)dimethylphenylsilane