Benzyl 2-bromo-2-phenylacetate

Base Information

Chemical Name:Benzyl 2-bromo-2-phenylacetate
CAS No.:74004-88-9
Molecular Formula:C₁₅H₁₃BrO₂
Molecular Weight:305.171
Hs Code.:
DSSTox Substance ID:DTXSID301298207
Nikkaji Number:J2.620.675H

Synonyms:benzyl 2-bromo-2-phenylacetate;SCHEMBL10691190;GCJIKSNIRBMITQ-UHFFFAOYSA-N;DTXSID301298207;Phenylmethyl I+/--bromobenzeneacetate;74004-88-9

Suppliers and Price of Benzyl 2-bromo-2-phenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Benzyl 2-bromo-2-phenylacetate

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:304.00989
Heavy Atom Count:18
Complexity:255

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)C(C2=CC=CC=C2)Br

Technology Process of Benzyl 2-bromo-2-phenylacetate

There total 4 articles about Benzyl 2-bromo-2-phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 62173-99-3,80409-16-1,97415-09-3,890-98-2
benzyl 2-hydroxy-2-phenylacetate

: 74004-88-9
2-bromo-2-phenylacetic acid benzyl ester

Guidance literature:: With phosphorus tribromide; In diethyl ether; at 20 ℃; for 2h;
DOI:10.1021/acs.orglett.1c03887

Reference yield: 87.0%

: 218792-82-6
α-diazo-α-phenylacetic acid benzyl ester

: 74004-88-9
2-bromo-2-phenylacetic acid benzyl ester

Guidance literature:: With cobalt(II) bromide hexahydrate; In 1,4-dioxane; at 100 ℃; for 1h; Inert atmosphere;
DOI:10.1002/adsc.202000009

Reference yield:

: 103-80-0
phenylacetyl chloride

: 74004-88-9
2-bromo-2-phenylacetic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: tetrachloromethane; bromine

2: tetrachloromethane

With tetrachloromethane; bromine;
DOI:10.1021/ja01192a069