(-)-(3R,5R)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine

Base Information

• Chemical Name: (-)-(3R,5R)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine
• CAS No.: 1448793-46-1
• Molecular Formula: C₁₁H₁₁F₄NO
• Molecular Weight: 249.208
• Mol file: 1448793-46-1.mol

Synonyms:(-)-(3R,5R)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine

Chemical Property of (-)-(3R,5R)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (-)-(3R,5R)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine

There total 1 articles about (-)-(3R,5R)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

(3S,5S)-rac-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine → (+)-(3S,5S)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine (1432511-70-0) + (-)-(3R,5R)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine (1448793-46-1)

Guidance literature:

With chiralpack AD; In ethanol; n-heptane;

DOI:10.1021/jm400225m