Technology Process of rac-β-(o-methoxyphenyl)-3-(triethylsilyl)-2,6-dideoxyglucose
There total 4 articles about rac-β-(o-methoxyphenyl)-3-(triethylsilyl)-2,6-dideoxyglucose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 73 percent / lithium diisopropylamide (LDA) / tetrahydrofuran / 2.5 h / -78 - 20 °C
2: 86 percent / Eu(fod)3 / CHCl3 / 12 h / 65 °C
3: 1.) borane-dimethylsulfide (BH3*DMS); 2.) hydrogen peroxide (H2O2), NaOH / 1.) methylene chloride, 0 deg C to room temp., 18 h; 2.) THF, 35 deg C, 1.5 h
With
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide; lithium diisopropyl amide;
Eu(fod)3;
In
tetrahydrofuran; chloroform;
DOI:10.1021/ja00291a031
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 86 percent / Eu(fod)3 / CHCl3 / 12 h / 65 °C
2: 1.) borane-dimethylsulfide (BH3*DMS); 2.) hydrogen peroxide (H2O2), NaOH / 1.) methylene chloride, 0 deg C to room temp., 18 h; 2.) THF, 35 deg C, 1.5 h
With
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide;
Eu(fod)3;
In
chloroform;
DOI:10.1021/ja00291a031
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 73 percent / lithium diisopropylamide (LDA) / tetrahydrofuran / 2.5 h / -78 - 20 °C
2: 86 percent / Eu(fod)3 / CHCl3 / 12 h / 65 °C
3: 1.) borane-dimethylsulfide (BH3*DMS); 2.) hydrogen peroxide (H2O2), NaOH / 1.) methylene chloride, 0 deg C to room temp., 18 h; 2.) THF, 35 deg C, 1.5 h
With
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide; lithium diisopropyl amide;
Eu(fod)3;
In
tetrahydrofuran; chloroform;
DOI:10.1021/ja00291a031
