C₃₃H₃₈N₃O₄

Base Information

• Chemical Name: C₃₃H₃₈N₃O₄
• CAS No.: 155637-99-3
• Molecular Formula: C₃₃H₃₈N₃O₄
• Molecular Weight: 540.682
• Mol file: 155637-99-3.mol

Synonyms:C₃₃H₃₈N₃O₄

Chemical Property of C₃₃H₃₈N₃O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₃₈N₃O₄

There total 2 articles about C₃₃H₃₈N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl (14691-88-4,78774-22-8) + Fmoc-Phe-ONSu (101214-43-1) → C33H38N3O4 (155637-99-3)

Guidance literature:

With triethylamine; In tetrahydrofuran; 1.) 0 deg C, 3 h, 2.) 24 deg C, 24 h;

DOI:10.1002/jps.2600830715

Reference yield:

N-Fmoc L-Phe (35661-40-6) → C33H38N3O4 (155637-99-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 20 h / 0 °C

2: 82 percent / Et₃N / tetrahydrofuran / 1.) 0 deg C, 3 h, 2.) 24 deg C, 24 h

With triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran;

DOI:10.1002/jps.2600830715

Reference yield: 82.0%

C33H38N3O4 (155637-99-3) → C18H28N3O2 (155638-02-1)

Guidance literature:

With potassium hydroxide; In methanol; at 25 ℃; for 1h;

DOI:10.1002/jps.2600830715

upstream raw materials:

4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl

Fmoc-Phe-ONSu

N-Fmoc L-Phe

Downstream raw materials:

C₁₈H₂₈N₃O₂