Benzenamine, 4-[(2R)-oxiranylmethoxy]- (9CI)

Base Information

• Chemical Name: Benzenamine, 4-[(2R)-oxiranylmethoxy]- (9CI)
• CAS No.: 457897-86-8
• Molecular Formula: C9H11 N O2
• Molecular Weight: 165.192
• Mol file: 457897-86-8.mol

Synonyms:Benzenamine,4-[(2R)-oxiranylmethoxy]- (9CI); (R)-Glycidyl p-aminophenyl ether

Chemical Property of Benzenamine, 4-[(2R)-oxiranylmethoxy]- (9CI)

Chemical Property:

• PSA: 47.78000
• LogP: 1.62760

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenamine, 4-[(2R)-oxiranylmethoxy]- (9CI)

There total 1 articles about Benzenamine, 4-[(2R)-oxiranylmethoxy]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(R)-1,2-epoxy-3-(4-nitrophenoxy)propane (125279-81-4) → (R)-glycidyl 4-aminophenyl ether (457897-86-8)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jm8002153

Reference yield: 70.0%

(R)-glycidyl 4-aminophenyl ether (457897-86-8) + methanesulfonyl chloride (124-63-0) → (R)-glycidyl N-methylsulfonyl-4-aminophenyl ether (457897-87-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;

DOI:10.1021/jm8002153

upstream raw materials:

(R)-1,2-epoxy-3-(4-nitrophenoxy)propane

Downstream raw materials:

(R)-glycidyl N-methylsulfonyl-4-aminophenyl ether

Refernces