[2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

Base Information

Chemical Name:[2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester
CAS No.:849670-34-4
Molecular Formula:C₂₂H₃₂FN₃O₄
Molecular Weight:421.512
Hs Code.:

Synonyms:[2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

Suppliers and Price of [2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

There total 3 articles about [2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 849671-39-2
(S)-carbonic acid 1-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester 4-nitro-phenyl ester

: N₁-(4-fluorophenyl)-ethane-1,2-diamine dihydrochloride

: 849670-34-4
[2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 18h;

Reference yield:

: 216086-95-2
(S)-3-cyclohexyl-2-hydroxy-1-morpholin-4-yl-propan-1-one

: 849670-34-4
[2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 4 h / 70 °C

2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 18 h / 20 °C

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; pyridine;

Reference yield:

: 27527-05-5
L-cyclohexylalanine

: 849670-34-4
[2-(4-fluoro-phenylamino)-ethyl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid; sodium nitrite / water / 17 h / 0 - 20 °C

2: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 20 °C

3: pyridine / 4 h / 70 °C

4: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 18 h / 20 °C

With sulfuric acid; N-ethyl-N,N-diisopropylamine; HATU; sodium nitrite; In tetrahydrofuran; pyridine; dichloromethane; water;