3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-1-(1-methylethyl)-2-oxo-4-propyl- (9CI)

Base Information

• Chemical Name: 3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-1-(1-methylethyl)-2-oxo-4-propyl- (9CI)
• CAS No.: 457604-61-4
• Molecular Formula: C12H16 N2 O2
• Molecular Weight: 220.26764
• Mol file: 457604-61-4.mol

Synonyms:3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-1-(1-methylethyl)-2-oxo-4-propyl- (9CI)

Chemical Property of 3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-1-(1-methylethyl)-2-oxo-4-propyl- (9CI)

Chemical Property:

• Boiling Point: 349.8±42.0 °C(Predicted)
• PKA: 3.89±0.58(Predicted)
• PSA: 66.02000
• Density: 1.15±0.1 g/cm3(Predicted)
• LogP: 1.95898

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-1-(1-methylethyl)-2-oxo-4-propyl- (9CI)

There total 1 articles about 3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-1-(1-methylethyl)-2-oxo-4-propyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-cyano-N-isopropylacetamide (52573-74-7) + ethyl butyroyl acetate (3249-68-1) → 1-isopropyl-4-propyl-2,6-dioxo-1,2,3,6-tetrahydropyridine-3-carbonitrile (457604-61-4)

Guidance literature:

With piperidine; at 100 ℃; for 20h;

DOI:10.1021/ja020168f

Reference yield:

N,N'-diphenylformamidine (864131-95-3) + 1-isopropyl-4-propyl-2,6-dioxo-1,2,3,6-tetrahydropyridine-3-carbonitrile (457604-61-4) → 1-Isopropyl-2,6-dioxo-5-[1-phenylamino-meth-(Z)-ylidene]-4-propyl-1,2,5,6-tetrahydro-pyridine-3-carbonitrile

Guidance literature:

With acetic anhydride; at 80 - 90 ℃; for 0.25h;

DOI:10.1021/ja020168f

upstream raw materials:

2-cyano-N-isopropylacetamide

ethyl butyroyl acetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 457604-61-4 3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-1-(1-methylethyl)-2-oxo-4-propyl- (9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send