ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate

Base Information

• Chemical Name: ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate
• CAS No.: 1290593-34-8
• Molecular Formula: C₃₆H₂₈N₈O₇S₂
• Molecular Weight: 748.8
• Mol file: 1290593-34-8.mol

Synonyms:ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate

Chemical Property of ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate

There total 3 articles about ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

1-(4-aminophenyl)-4-benzoyl-5-phenyl-N-(5-sulphamoyl-1,3,4-thiadiazole-2-yl)-1H-pyrazole-3-carboxamide (1161947-50-7) + ethyl 3-oxo-3-phenylpropionate (94-02-0) → ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate (1290593-34-8)

Guidance literature:

1-(4-aminophenyl)-4-benzoyl-5-phenyl-N-(5-sulphamoyl-1,3,4-thiadiazole-2-yl)-1H-pyrazole-3-carboxamide; With hydrogenchloride; sodium acetate; sodium nitrite; In water; at 0 - 5 ℃;

ethyl 3-oxo-3-phenylpropionate; In ethanol; water;

DOI:10.3109/14756366.2010.491795

Reference yield:

4-benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (658081-76-6) → ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate (1290593-34-8)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride

2: hydrogenchloride; sodiumsulfide nonahydrate / water

3: hydrogenchloride; sodium acetate; sodium nitrite / water / 0 - 5 °C

With hydrogenchloride; thionyl chloride; sodiumsulfide nonahydrate; sodium acetate; sodium nitrite; In water;

DOI:10.3109/14756366.2010.491795

Reference yield:

C25H17N7O6S2 (1100715-17-0) → ethyl 2-(2-(4-(4-benzoyl-5-phenyl-3-((5-sulphamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)-3-oxo-3-phenylpropanoate (1290593-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; sodiumsulfide nonahydrate / water

2: hydrogenchloride; sodium acetate; sodium nitrite / water / 0 - 5 °C

With hydrogenchloride; sodiumsulfide nonahydrate; sodium acetate; sodium nitrite; In water;

DOI:10.3109/14756366.2010.491795

upstream raw materials:

C₂₅H₁₇N₇O₆S₂

1-(4-aminophenyl)-4-benzoyl-5-phenyl-N-(5-sulphamoyl-1,3,4-thiadiazole-2-yl)-1H-pyrazole-3-carboxamide

ethyl 3-oxo-3-phenylpropionate

4-benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid