N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Base Information

Chemical Name:N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride
CAS No.:1180486-50-3
Molecular Formula:C₂₄H₂₅F₆N₃O₄S*ClH
Molecular Weight:601.998
Hs Code.:

N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Synonyms:N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Suppliers and Price of N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

There total 10 articles about N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 474554-46-6
5,6-diethoxy-7-fluoro-3H-isoindol-1-ylamine

: 1180486-92-3
N-[3-(2-bromoacetyl)-5-pentafluorosulfanylphenyl]cyclopropylamide

: 1180486-50-3
N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Guidance literature:: 5,6-diethoxy-7-fluoro-3H-isoindol-1-ylamine; N-[3-(2-bromoacetyl)-5-pentafluorosulfanylphenyl]cyclopropylamide; In N,N-dimethyl-formamide; at 20 - 25 ℃; Inert atmosphere;

With hydrogenchloride; In water;

Reference yield:

: 833-96-5
3-(pentafluoro-λ⁶-sulphanyl)benzoic acid

: 1180486-50-3
N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Guidance literature:: Multi-step reaction with 10 steps

1.1: nitric acid; sulfuric acid / 20 - 75 °C / Inert atmosphere

2.1: thionyl chloride / 10 h / Reflux; Inert atmosphere

3.1: N,N-diethyl-N-isopropylamine / dichloromethane / 1 h / 20 - 25 °C / Inert atmosphere

4.1: hydrogen / Raney nickel / methanol / 5 h / Inert atmosphere

5.1: triethylamine / dichloromethane / 20 - 25 °C / Inert atmosphere

6.1: lithium hexamethyldisilazane / tert-butyl methyl ether; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

6.2: 0 - 25 °C / Inert atmosphere

7.1: sulfuric acid / acetonitrile; water / 20 - 75 °C / Inert atmosphere

7.2: pH 7

8.1: triethylamine / dichloromethane / 2 h / Inert atmosphere

9.1: phenyltrimethylammonium tribromide / tetrahydrofuran; methanol / 20 - 50 °C / Inert atmosphere

10.1: N,N-dimethyl-formamide / 20 - 25 °C / Inert atmosphere

With thionyl chloride; N,N-diethyl-N-isopropylamine; sulfuric acid; hydrogen; nitric acid; phenyltrimethylammonium tribromide; triethylamine; lithium hexamethyldisilazane; Raney nickel; In tetrahydrofuran; methanol; dichloromethane; tert-butyl methyl ether; water; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 852469-45-5
3-nitro-5-(pentafluoro-λ⁶-sulfanyl)benzoic acid

: 1180486-50-3
N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]cyclopropanecarboxamide hydrochloride

Guidance literature:: Multi-step reaction with 9 steps

1.1: thionyl chloride / 10 h / Reflux; Inert atmosphere

2.1: N,N-diethyl-N-isopropylamine / dichloromethane / 1 h / 20 - 25 °C / Inert atmosphere

3.1: hydrogen / Raney nickel / methanol / 5 h / Inert atmosphere

4.1: triethylamine / dichloromethane / 20 - 25 °C / Inert atmosphere

5.1: lithium hexamethyldisilazane / tert-butyl methyl ether; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

5.2: 0 - 25 °C / Inert atmosphere

6.1: sulfuric acid / acetonitrile; water / 20 - 75 °C / Inert atmosphere

6.2: pH 7

7.1: triethylamine / dichloromethane / 2 h / Inert atmosphere

8.1: phenyltrimethylammonium tribromide / tetrahydrofuran; methanol / 20 - 50 °C / Inert atmosphere

9.1: N,N-dimethyl-formamide / 20 - 25 °C / Inert atmosphere

With thionyl chloride; N,N-diethyl-N-isopropylamine; sulfuric acid; hydrogen; phenyltrimethylammonium tribromide; triethylamine; lithium hexamethyldisilazane; Raney nickel; In tetrahydrofuran; methanol; dichloromethane; tert-butyl methyl ether; water; N,N-dimethyl-formamide; acetonitrile;